对于晚期卵巢癌肿瘤细胞减灭术达到R0切除，是改善晚期卵巢癌患者预后的最关键因素。手术能否达到R0主要取决3个因素：肿瘤扩散情况，患者身体状况和手术团队能力。R0切除是极其复杂并且需要多学科高度协作的系统工程，需要重视个体化治疗原则，包括选择合适的手术时机，合理的手术方式，足够的手术范围才能达到满意的肿瘤细胞减灭术。

Achieving R0 resection during cytoreductive surgery for advanced ovarian cancer represents the most critical factor for improving patient prognosis. The success of R0 resection primarily depends on three factors： the extent of disease spread，the patient's overall condition，and the surgical team's expertise. R0 resection is an extremely complex systematic procedure and requires high degree of multidisciplinary collaboration. Emphasizing an individualized treatment approach—including selecting the optimal timing for surgery，the appropriate surgical technique，and the sufficient extent of resection—is essential to achieving satisfactory cytoreduction.