中国实用妇科与产科杂志

中国实用妇科与产科杂志

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黄体期促排卵的利弊分析

  

  1. 中山大学附属第一医院生殖医学中心，广东 广州  510080
  • 出版日期:2021-04-02 发布日期:2021-04-19
  • 通讯作者: 黄珈
  • 基金资助:
    国家重点研发计划（2016YFC1000205）

Pros and cons of luteal phase stimulation.

  1. Reproductive Medicine Center，the First Affiliated Hospital，Sun Yat-sen University，Guangzhou 510080，China
  • Online:2021-04-02 Published:2021-04-19

摘要： 随着胚胎冷冻技术的不断进步及全胚冷冻策略的推广，卵巢刺激方案获得许多新进展。利用内源性高孕激素的黄体期促排卵，应用外源性孕激素类药物的卵泡期高孕激素状态下促排卵，及其衍生而来的一系列方案已被证明能有效抑制黄体生成素（luteinizing hormone，LH）峰，且能获得高质量的胚胎及临床活产，简单方便，经济有效。文章就黄体期促排卵方案的原理、优缺点及临床应用等方面进行讨论。

关键词: 黄体期促排卵, 卵泡期高孕激素状态下卵巢刺激, 双刺激, 卵巢刺激方案, 体外受精-胚胎移植

Abstract: Luteal phase ovarian stimulation is a new stimulation protocol in recent years. The use of progesterone during ovarian stimulation is effective to block the LH surge. There are two ways of using progesterone，as with luteal phase stimulation，or with the progestin primed ovarian stimulation. A variety of stimulation protocols are derived from these two methods. The principles of these protocols，their potential in clinical practice and their medical significance remain to be demonstrated. Their putative advantages and disadvantages are summarized here.

Key words: luteal phase stimulation, progestin primed ovarian stimulation, double stimulation, ovarian stimulation protocol, IVF-ET

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