中国实用妇科与产科杂志
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摘要： LACC研究结果提示对于早期子宫颈癌患者，接受微创手术相比于开腹手术的患者有更高的复发率和更低的生存率。基于该研究结果，目前包括安德森癌症中心在内的国内外医疗机构均已停止或减少对ⅠA2～ⅠB1期子宫颈癌患者提供微创手术。文章在回顾LACC试验结果的同时，分析了目前妇科肿瘤学界对LACC研究结论存在的疑问及微创手术的改良空间，探讨了随机对照试验的临床价值及中国现状。
关键词: 子宫颈肿瘤, 微创手术, 随机对照临床研究, LACC
Abstract: LACC study showed that early-stage cervical cancer patients who underwent minimally invasive surgery had higher recurrence rates and worse overall survival compared to those that underwent open radical hysterectomy.Based on these research results，multitudinous medical institutions at home and abroad，include MD Anderson cancer center，had stopped or reduced laparoscopic radical hysterectomy for stage IA2-IB1 cervical cancer.In this report，we reviewed the LACC trial findings in depth，and investigated gynecologic oncologists’ questions on the unexpected results.Besides，we also explored the clinical significance of randomized controlled trial in the study of malignant tumor such as cervical cancer and the current status of China.
Key words: cervix neoplasms, minimally invasive surgery, randomized controlled trial, LACC
中图分类号:
R737.3
屈庆喜，张远丽. LACC临床随机对照试验研究的启示[J]. 中国实用妇科与产科杂志, DOI: 10.19538/j.fk2020040108.
QU Qing-xi，ZHANG Yuan-li. What we learned in LACC study.[J]. Acta Metallurgica Sinica, DOI: 10.19538/j.fk2020040108.
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https://www.zgsyz.com/zgsyfck/CN/Y2020/V36/I4/320
