中国实用妇科与产科杂志
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摘要: 绝经增加了绝经后女性患心血管疾病的风险,绝经激素治疗(MHT)不仅能有效缓解更年期血管舒缩等症状,还可以改善心血管疾病发展的中间指标,从而减少围绝经期女性心血管疾病的发生。目前多项临床研究结果表明,对绝经后10年内和60岁以下健康女性在围绝经期开始MHT,心血管疾病发生率和死亡率有所下降。目前缺少MHT能够改善已确诊的心脏疾病的最终证据,不推荐MHT用于心血管疾病的一级预防,也不应用于冠心病的二级预防。
关键词: 绝经激素治疗, 心血管疾病, 绝经
Abstract: Menopause increases the risk of cardiovascular disease in postmenopausal women.Menopause hormone therapy can not only effectively relieve symptoms such as menopause vasomotor,but also improve the intermediate indicators of cardiovascular disease development,so as to reduce the incidence of cardiovascular disease in perimenopausal women.A number of clinical studies have shown that the incidence and mortality of cardiovascular diseases have decreased for healthy women who start hormone therapy in perimenopausal period within 10 years after menopause and below 60 years old.At present,there is still a lack of conclusive evidence that MHT can improve the diagnosed heart disease.Therefore,MHT is not recommended for primary prevention of cardiovascular disease,nor is it for secondary prevention of coronary heart disease.
Key words: menopause hormone therapy, cardiovascular disease, menopause
中图分类号:
R711.75
刘艳华,杨欣. 绝经激素治疗与心血管疾病[J]. 中国实用妇科与产科杂志, DOI: 10.19538/j.fk2020030106.
LIU Yan-hua,YANG Xin. Menopausal hormone therapy and cardiovascular disease.[J]. Acta Metallurgica Sinica, DOI: 10.19538/j.fk2020030106.
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