To improve the treatment and long-term management of systemic sclerosis（SSc），the European Alliance of Associations for Rheumatology（EULAR） released updated SSc treatment guidelines in September 2024，following the 2017 guidelines. These updated guidelines continue the previous organ-targeted treatment strategies and introduce several key recommendations across eight major domains，including Raynaud’s phenomenon，digital ulcers，and pulmonary arterial hypertension. Most of the new recommendations are related to skin fibrosis and interstitial lung disease（ILD）. This article provides an interpretation of the main content of the guidelines for clinical reference.

systemic sclerosis, EULAR, treatment guidelines

为提高系统性硬化症（systemic sclerosis，SSc）的治疗及长期管理水平，继2017年发布的 SSc 指南后，欧洲抗风湿病联盟（European Alliance of Associations for Rheumatology，EULAR）于2024年9月发布了新的 SSc 治疗指南，该指南延续了过去指南针对靶器官的治疗策略，增加多项重点推荐内容，涵盖了包括雷诺现象、指端溃疡、肺动脉高压等8个主要分类。大多数新建议与皮肤纤维化和肺间质病变（ILD）有关。文章对指南主要内容进行了解读，供临床借鉴和参考。

系统性硬化症, 欧洲抗风湿病联盟, 治疗指南