Abstract:

Abstract：Objective　To study the diffusion-weighted magnetic resonance imaging （DWI） in preterm children with periventricular leukomalacia diagnosis. Methods　we collected suspected PVL children with hypoxia who were treated in the First Affiliated Hospital of Xinjiang Medical University NICU from January 2008 to January 2009. The 55 cases who accept ultrosound inspection are divided into PVL group （15 cases） and control group （40 cases）. Simultaneously we used DWI to examine all of the infants and tested ADC value in order to analysis the sensitivity and specificity. Results　The sensitivity was 66.7%，specificity was 95%. Conclusion　DWI can be used as a premature imaging method in children in the early diagnosis of PVL.

Key words: premature infants, periventricular leukomalacia, ultrasonography diffusion-weighted magnetic resonance imaging

摘要：

目的　探讨弥散加权核磁成像（DWI）对早产儿脑室周围白质软化（PVL）的诊断价值。方法　收集2008年1月至2009年8月因缺氧而收住新疆医科大学第一附属医院重症监护室（NICU）疑似PVL的早产儿55例，对其进行头颅B超检查，并将患儿分为PVL组（15例）及对照组（40例），同步行DWI检查并测定弥散系数（ADC值），分析DWI诊断早产儿PVL的灵敏度和特异度等。结果　DWI诊断PVL的灵敏度为66.7%，特异度为95.0%。结论　DWI可以作为早期诊断早产儿PVL的影像学检查方法。

关键词: 早产儿, 脑室周围白质软化, 头颅B超, 弥散加权核磁成像