Abstract:

Objective　To discuss the variation of parameters of heart rate variability  in neurally mediated syncope （NMS） in children. 

Methods　Twenty-nine children with NMS （11 males and 18 females， mean age 12.4±2.2 yrs） who came from Peking University First Hospital

from April 2007 to March 2008，were included in the study. The hemodynamic patterns of NMS were detected. All patients experienced 24 hours

of Holter monitoring. Parameters of heart rate variability in children with NMS were analyzed. SPSS 10.0 software was used for the

statistical analysis of these data. Results　There was no significant difference in SDNN between that of NMS group and normal value （P >

0.05）. The SDNNi and rMSSD in NMS group increased by 19.21% and 54.07%， respectively （P < 0.05）. The pNN50 and triangular index were not

significantly different between NMS group and normal value （P > 0.05）.  Conclusion　There is autonomic nerve adjustment imbalance in

children with NMS.

Key words: neurally mediated syncope； heart rate variability； children

摘要：

探讨自主神经介导性晕厥（NMS）患儿心率变异性的变化。 方法　2007年4月至2008年3月在北京大学第一医院儿科就诊的NMS患儿29例，其中男11例，女18例；年龄8～17岁，平均（12.4±2.2）岁。所有患儿进行24h Holter监测。比较患儿心率变异性中的各项参数变化。采用SPSS10.0软件进行统计。结果　NMS组的窦性心搏间期标准差（SDNN）值与正常值相比，差异无统计学意义（P > 0.05）； 窦性心搏间期标准差的均值（SDNNi）与正常值相比增加了19.21%（P< 0.05），rMSSD值与正常值相比增加了54.07%（P < 0.05），相邻的NN间期之差大于50ms 的心搏数占总心搏数的百分率（pNN50）及三角指数值与正常值相比差异均无统计学意义（P > 0.05）。 结论　NMS患儿存在自主神经功能调节失衡。

关键词: 自主神经介导性晕厥, 心率变异性, 儿童