中国实用儿科杂志

中国实用儿科杂志 ›› 2026, Vol. 41 ›› Issue (4): 343-347.DOI: 10.19538/j.ek2026040614

• 疑难病例大查房 • 上一篇    下一篇

难治性Graves病1例治疗探索及长期随访

  

  1. 国家儿童医学中心(北京)  首都医科大学附属北京儿童医院内分泌遗传代谢科，北京  100045
  • 出版日期:2026-04-06 发布日期:2026-05-18
  • 通讯作者: 巩纯秀，电子信箱：chunxiugong@163.com

Treatment exploration and long-term follow-up of a case of refractory Graves’ disease

  1. Department of Endocrinology，Genetics and Metabolism，National Center for Children’s Health（Beijing），Beijing Children’s Hospital，Capital Medical University，Beijing  100045，China
  • Online:2026-04-06 Published:2026-05-18

摘要： 文章重点讨论了1例难治复发性Graves’病患儿治疗及长期随访结果，患儿历时9年先后予甲巯咪唑、丙硫氧嘧啶治疗，曾3年内复发3次，表现为难治性及复发性，经多学科协作（multidisciplinary teamwork，MDT）会诊后，先后3次行超声引导下甲状腺微波消融术，至末次随访时已达临床治愈，甲状腺功能维持正常，未再复发。

关键词:

Abstract: This article focuses on the treatment and long-term follow-up results of a pediatric patient with refractory and recurrent Graves’ disease，who was treated with methimazole and propylthiouracil sequentially in 9 years and experienced three relapses within three years. The disease is refractory and recurrent. With multidisciplinary teamwork（MDT）， the patient underwent three sessions of ultrasoundguided thyroid microwave ablation. At the last follow-up，the patient has been cured clinically，with normal thyroid function and no further relapse.

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