中国实用儿科杂志

中国实用儿科杂志 ›› 2025, Vol. 40 ›› Issue (5): 437-440.DOI: 10.19538/j.ek2025050617

• 病例报告 • 上一篇    

青少年慢性复发性多灶性骨髓炎1例

  

  1. 1.山东第二医科大学临床医学院，山东  潍坊 261000；2.淄博市中心医院风湿免疫科，山东  淄博  255020；3.淄博市妇幼保健院内分泌科，山东  淄博  255020；4.山东大学附属儿童医院感染性疾病科，山东  济南  250000
  • 出版日期:2025-05-06 发布日期:2025-08-28
  • 通讯作者: 张秀英，电子信箱：zbzhxy@126.com

Chronic recurrent multifocal osteomyelitis in an adolescent：a case report

  1. School of Clinical Medicine，Shandong Second Medical University，Weifang  261000，China
  • Online:2025-05-06 Published:2025-08-28

摘要： 慢性复发性多灶性骨髓炎（CRMO）为罕见疾病，临床医师对该病的认识尚不充分，导致临床上易漏诊或误诊为感染、肿瘤或儿童生长痛等，从而延误治疗并影响患儿预后。目前，该病在国内的报道尚较少。该文回顾性报道2023-12-18淄博市中心医院风湿免疫科收治的1例被误诊长达7年余的青少年CRMO病例，同时结合文献进行分析，以期提高临床医生对该病的认识。

关键词: 慢性复发性多灶性骨髓炎, 自身炎性骨病, 肿瘤坏死因子α抑制剂

Abstract: Chronic recurrent multifocal osteomyelitis is a rare clinical disease with insufficient clinical recognition.It is often misdiagnosed as infectious osteomyelitis，bone tumors，or childhood growing pain，etc，whichdelays treatment and affectsatient prognosis.Currently，there are few reports of this disease in China. A case of juvenile CRMO who was misdiagnosed for more than 7 years in the rheumatology and Immunology Department of Zibo Central Hospital was retrospectively reported in this paper，and the literature was analyzed to improve the understanding of the disease among clinicians.

Key words: chronic recurrent multifocal osteomyelitis, autoinflammatory bone disease, tumor necrosis factor alpha inhibitors