中国实用儿科杂志

中国实用儿科杂志 ›› 2025, Vol. 40 ›› Issue (5): 381-385.DOI: 10.19538/j.ek2025050606

• 专题笔谈 • 上一篇    下一篇

儿童白癜风的外用药治疗进展

  

  1. 天津市儿童医院皮肤科  天津市儿科研究所  天津市儿童出生缺陷防治重点实验室， 天津  300134
  • 出版日期:2025-05-06 发布日期:2025-08-28
  • 通讯作者: 李钦峰，电子信箱：lyz20061217@sina.com
  • 基金资助:
    天津大学“医学+”专项基金（22JCYBJC01420）

Progress of topical treatment for vitiligo in children

  1. Department of Dermatology，Tianjin Children′s Hospital，Tianjin Key Laboratory of Birth Defects for Prevention and Treatment，Tianjin 300134，China
  • Online:2025-05-06 Published:2025-08-28

摘要： 白癜风是一种常见慢性自身免疫性、色素脱失性皮肤病，其治疗方法包括局部外用药物、系统治疗、光疗、外科手术治疗等。随着近年来对白癜风发病机制的研究越来越深入，许多新型外用药如Janus激酶抑制剂、磷酸二酯酶-4抑制剂、前列腺素F2α衍生物、假过氧化氢酶/超氧化物歧化酶等逐步尝试用于白癜风的治疗，并取得较好的临床疗效。该文旨在对简要阐述外用药在儿童白癜风治疗中的进展。

关键词: vitiligo, drug therapy, child, topical drugs

Abstract: Vitiligo is a common chronic autoimmune and depigmented skin disease. Its treatment methods include topical drugs，systemic therapy，phototherapy，surgical treatment and so on.In recent years，with more and more in-depth research on the pathogenesis of vitiligo，many new external drugs，such as Janus kinase inhibitors，phospodi-esterase-4 inhibitors，prostagland in F2α derivatives，and pseudocatalase/superoxide dismutase，have been gradually tried in the treatment of vitiligo，and have achieved good clinical efficacy. The objective of this article is to briefly review the progress of topical agents in the treatment of vitiligo in children.

Key words: 白癜风, 药物治疗, 儿童, 外用药