中国实用儿科杂志

中国实用儿科杂志 ›› 2023, Vol. 38 ›› Issue (11): 838-842.DOI: 10.19538/j.ek2023110607

• 专题笔谈 • 上一篇    下一篇

生长激素治疗儿童特发性矮身材的研究进展

  

  1. 福建医科大学附属福州儿童医院内分泌遗传代谢科，福建  福州  350000
  • 出版日期:2023-11-06 发布日期:2023-11-02
  • 通讯作者: 陈瑞敏，电子信箱：chenrm321@sina.com

History of growth hormone in the treatment of idiopathic short stature

  1. Department of Endocrinology，Genetics and Metabolism，Fuzhou Children's Hospital，Fujian Medical University，Fuzhou  350000，China
  • Online:2023-11-06 Published:2023-11-02

摘要： 特发性矮身材（idiopathic short stature，ISS）是一组病因未明的矮身材疾病的总称。人们对ISS的认识最早可追溯至20世纪70年代。生长激素（growth hormone，GH）已被美国、比利时、瑞典、中国等国家批准用于改善ISS患儿身高。该文回顾了对ISS的认识过程及介绍GH治疗ISS的历史进程、以期为临床工作提供参考。

关键词: 特发性矮身材, 生长激素, 治疗

Abstract: Idiopathic short stature （ISS） is a general term of a group of short stature diseases of unknown etiology，The recognition to ISS can be traced back to the 1970s. Growth hormone （GH） has been approved by countries such as the United States，Belgium，Sweden，and China to be used used to improve the height of children with ISS.  In this article，the history of recognition and treatment of GHin ISS is reviewed，in order to provide reference for clinical work.

Key words: idiopathic short stature, growth hormone, treatm-ent