关键词: 儿童, 嗜酸细胞性胃肠炎, 糖皮质激素, 饮食疗法, 抗过敏治疗

Abstract:

Objective    To approach the diagnosis and treatment of eosinphilic gastroenteritis in children. Methods    In 12 cases of children with eosinophilic gastroenteritis in Nanjing Children's Hospital Affiliated to Nanjing Medical University from May 2009 to Nov.2011，the clinical manifestations，laboratory data，endoscopic and pathological findings and treatment were collected and analyzed. Results    In the 12 patients，mucosal type was present in 8 cases，muscle-type in 1 case，and serous type in 3 cases. Most of the pediatric eosinophilic gastroenteritis had no specific clinical manifestations. From direct endoscopic vision，edema and erosion were the main performance of gastrointestinal mucosa. Histopathologic examination revealed that there was dense infiltration in gastrointestinal mucosa lamina propria by eosinophils. The effects of dietetic and antianaphylactic treatments were good. Conclusion    The clinical manifestations of pediatric eosinophilic gastroenteritis are various and nonspecific. The dietetic and antianaphylactic treatments have obvious therapeutic effect . About 1 to 2 weeks of glucocorticoids therapy can rapidly alleviate the symptoms，and it continues for 3 months by reducing the dosage gradually.

Key words: children, eosinophilic gastroenteritis, glucocorticoids, dieteic treatments, antianaphylactic treatments