关键词: 过敏性紫癜, 胃镜检查（术）, 儿童

Abstract:

Objective　To study the gastroscopical features and to evaluate the application value of gastroscopy to early diagnosis of Henoch-Schonlein purpura（HSP） in children. Methods　There were 79 children involved in a retrospective analysis，who underwent gastroscopy and had HSP as final diagnosis between January 2009 and May 2010 in Children’s Hospital of Chongqing Medical University. Results　Gastroscopic findings included diffused congestive edema，widespread erosions and ulcerations in gastroduodenal mucosa while the mucosal ecchymosis highlighted the pathological changes，which were similar to the purpura in skin. More distal the gastroscopy reached along upper gastrointestinal track，more severe the mucosal lesions manifested，as was especially significant in descending duodenum．To respond to clinical requirements，we pushed the gastroscope-tip to jejunum-input in one of all 79 cases. Conclusion　Typical endoscopic findings in gastroduodenal mucosa helps to make early diagnosis of HSP，especially HSP without purpura；gastroscopy can show the severity of gastrointestinal mucosal damages and be a guidance to clinical therapy. Finally，what we have to highlight is that it’s necessary to make the gastroscope-tip reach jejunum-input for higher detection rate during the gastroscopic operation in early diagnosis of HSP in children.

Key words: Henoch-Schonlein purpura（HSP）, gastroscopy, children