中国实用儿科杂志

中国实用儿科杂志

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唇腭裂患儿中先天性心脏病的发生率及其特点

虢艳，于明华，刘特长，张丽，王洪涛，邓细河，黎凡，崔颖秋   

  1. 广州市儿童医院，广东广州 510120
  • 收稿日期:2005-11-12 修回日期:2006-02-05 出版日期:2006-06-06 发布日期:2006-06-06

Prevalence of congenital heart diseases in patients with oral cleft palate in Guangdongprovince.

Guo Yan，Yu Minghua，Liu Techang，et al.   

  1. Guangzhou Children’s Hospital,GuangZhou 510120,China
  • Received:2005-11-12 Revised:2006-02-05 Online:2006-06-06 Published:2006-06-06

摘要： 目的探讨唇腭裂患儿中先天性心脏病(简称先心病)的发生率及其特点。 方法广州市儿童医院口腔科2004-01—2005-05共收治567例拟行唇腭裂修复术的患儿，将患儿分成单纯唇裂组、单纯腭裂组及唇裂合并腭裂组3组，对3组患儿均行彩色多普勒超声心动图检查，对检查结果进行统计学分析。 结果567例唇腭裂患儿中共检出先天性心脏病37例，总发生率为653%，主要的先心病为：房间隔缺损(ASD)、动脉导管未闭(PDA)、室间隔缺损(VSD)；其中单纯唇裂组和单纯腭裂组患儿先心病发生率分别为508%、1056%，唇裂合并腭裂组患儿先心病发生率为521%。运用Pearson卡方检验进行统计学分析，3组患儿的先心病发生率差异无显著性。 结论先心病在唇腭裂患儿中发生率较高，彩色多普勒超声心动图检查能清楚准确地诊断各类型的先天性心脏病，可用于唇腭裂修复术前的常规检查。

关键词: 先天性心脏病, 唇腭裂, 发生率

Abstract: AbstractObjectiveTo explore the prevalence of congenital heart disease (CHD) in cleft patients. MethodsFrom Jan.2004 to May 2005,a colour Doppler echocardiogram was performed on 567 patients with oral cleft palate in Guangzhou Children's Hospital.The results were analysed with statistics. ResultsThirtyseven patients were found to have CHD in 567 patients (653%);6 cases of them occurred in group with cleft lip (521%),15 patients occurred in the group of cleft palate(1056%),and 16 patients occurred in the group of cleft lip and palate (554%).Atrial septal defects(ASD),patent ductus arteriosus(PDA) and ventricular septal defects(VSD) were the commonst malformation in the study. ConclusionThe prevalence of CHD in cleft patients is high.Color Doppler echocardiography is a useful and reliable tool in diagnosing CHD in patients with oral cleft palate of all kinds’ CHDS.

Key words: Left lip and palate, Prevalence