| [1］Tian YF，Hsieh CH，Hsieh YJ，et al.α-Lipoic acid prevents mild portal endotoxaemia-induced hepatic inflammation and β cell dysfunction［J］.Eur J Clin Invest，2012，42(6)：637-648. [2］付裕.硫辛酸联合甲钴胺治疗糖尿病周围神经病变的临床观察［J］.中国实用内科杂志，2008,28（1）：81-83. [3］Lee BW，Kwon SJ，Chae HY，et al.Dose-related cytoprotective effect of alpha-lipoic acid on hydrogen peroxide-induced oxidative stress to pancreatic beta cells［J］.Free Radic Res，2009，43(1)：68-77. [4］Eltrickl J，Docherty k.Phosphorylation 2 dependent nucleo-cytoplasmic shuttling of pancreatic duodenal homeobox 21［J］.Diabetes，2001，50：2244-2252. [5］Kaneto H Xu G，Song KH，et al.Activation of the hexosamine pothway leads to deterioration of pancreatic β-cell function through the induction of oxidative stress［J］，J Biol chem，2001，276：31099-31104. [6］Kaneto H，Kajimoto Y，Fujitani T，et al.Oxidative stress induces p21 expression in pancreatic is let cells：possible in plication in beta-cell dysfunction［J］.diabetologia，1999，42：1093-1097. [7］Janciaukiene S，Ahren B.Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptare in correlotion with cytotoxicity in two insulin-producing cell lines［J］.Biochem Biophys Res Commun，2000，267：619-625. [8］Kobayashi T，Tsunawakis S,Sequchi H.Evaluation of the processfor superoxide production by NADPH Oxidase in human neutrophils：evidence for cytoplasmic origin of superoxide ［J］.Redox Rep，2001，6(1)：27-36. [9］刘赫，刘国良.α-硫辛酸在糖尿病领域中的临床应用［J］.实用糖尿病杂志，2007，3：12-14. [10］Shen W，Liu K，Tian C，et al.Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid［J］.J Cell Biochem，2008，104(4)：1232-1243. |
