中国实用内科杂志

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老年终末期肾脏疾病肾脏替代治疗的选择

徐天华刘芳婕姚丽   

  1. 作者单位:中国医科大学附属第一医院肾内科,沈阳 110001
  • 出版日期:2014-12-01 发布日期:2014-12-19
  • 通讯作者: 姚丽
  • 作者简介:姚丽,医学博士后、主任医师、教授。中国医科大学附属第一医院肾内科副主任。兼任中华医学会肾脏病学分会青年委员、中华医学会肾脏病学分会血液净化学组专家组成员、中国女医师协会肾脏病医学专家委员会常委、辽宁省肾脏病学分会委员兼秘书等;《中国实用内科杂志》等多种期刊编委。先后主持及参与多项国家、省部级课题,在国内外专业杂志发表论文30余篇,参编全国高等学校医学规划教材及肾脏病学专著。
  • 基金资助:

    国家“十二五”科技支撑计划项目子课题(2011BAI10B02);辽宁省科技厅社会发展攻关计划(2013225303);辽宁省教育厅高等学校科研项目(L2011134)

Renal replacement therapy in elderly patients with end-stage renal disease

XU Tian-huaLIU Fang-jieYAO Li.   

  1. Department of Nephrology,the First Affiliated Hospital of China Medical University,Shenyang 110001,China
  • Online:2014-12-01 Published:2014-12-19

摘要:

老年终末期肾脏疾病的发病率和患病率逐年增加。老年患者有其特有的病理生理学特点和临床表现,常同时存在营养不良以及其他器官的病变,如心脏、脑血管疾病,对容量负荷增加的耐受性差。与年轻患者相比,在治疗过程中更容易出现合并症,影响老年患者的生存质量和生存期。开始替代治疗的时机以及适当的个体化治疗方式对老年终末期肾病患者至关重要。血液透析、腹膜透析以及肾移植都是可以选择的替代治疗方式,要综合考虑老年患者的疾病情况、家庭状况、经济条件以及社会因素等进行选择。

关键词: 老年终末期肾病, 血液透析, 腹膜透析, 肾移植

Abstract:

Abstract:The incidence and prevalence of end-stage renal disease in elderly patients have been increasing rapidly in recent years.Previous studies have pointed out special physiopathological characteristics and clinical manifestations in elderly patients.These patients often suffer from malnutrition and multiple extra-renal comorbidities such as cardiovascular and cerebrovascular diseases.Most studies showed that the quality of life and survival of the elderly dialyzed patients were worse than those of younger patients because of multiple comorbidities.However,hemodialysis,peritoneal dialysis and kidney transplantation are elective model for the elderly,and the choice of treatment model depends on the individual,clinical,economic conditions and social factors.

Key words: elderly patients with end-stage renal disease, hemodialysis, peritoneal dialysis, kidney transplantation

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