中国实用内科杂志 ›› 2012, Vol. 32 ›› Issue (12): 921-924.

• 指南论坛 • 上一篇    下一篇

KDIGO指南解读:狼疮性肾炎治疗

付平,秦伟   

  1. 作者单位:四川大学华西医院肾脏内科,成都 610041
  • 出版日期:2012-12-01 发布日期:2012-11-22

Treatment of lupus nephritis:interpretation of KDIGO guideline.

FU Ping,QIN Wei   

  1. Division of Nephrology,West China Hospital,Sichuan University,Chengdu 610041, China
  • Online:2012-12-01 Published:2012-11-22

摘要:

狼疮性肾炎(LN)在我国发病率相对较高,患者个体差异大,同时各医疗中心的治疗选择不尽相同,不利于LN患者的规范化治疗。2011年,国际改善全球肾脏病预后组织(KDIGO)颁布的肾小球肾炎临床诊疗指南,对LN的治疗在组织病理分型基础上做了详细的阐述。本文以KDIGO指南为基础,结合临床实际以及其他组织新发布的指南,就中国LN患者的一般治疗及免疫抑制治疗提出新的解读。

关键词: KDIGO指南, 狼疮性肾炎, 系统性红斑狼疮

Abstract:

The 2011 Kidney Disease: Improving Global Outcome (KDIGO) guideline has delineated the treatment of lupus nephrits (LN) based on pathological classification of glomerulonephritis.The comparatively high prevelence of LN,varying betweenindividual difference and various treatment protocols among institutions in China may have hampered standarization of therapy.On the basis of KDIGO guideline,the present review targeted at interpreting general treatment protocols and administration of immunosuppressants in Chinese patients with LN by means of integrating with routine clinical practice and latest guidelines released by miscellaneous organizations.

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Key words: KDIGO guideline, lupus nephritis, systemic lupus erythematosus

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