中国实用内科杂志

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FibroScan用于慢性肝病临床诊治新进展

曾祥华石代蓉王宇明   

  1. 作者单位:第三军医大学西南医院全军感染病研究所, 重庆 400038
  • 出版日期:2014-12-01 发布日期:2014-12-19
  • 通讯作者: 王宇明
  • 作者简介:王宇明,医学博士后、教授、主任医师、博士生导师。担任生物技术临床应用委员会及中国中西医结合学会传染病分会副主任委员,中华医学会感染病分会常务委员、中国医师协会感染病分会副会长、中华医学会感染病学分会病毒性肝炎学组组长等;为20余家国内外著名杂志编委、常委编委或副主编。先后承担国家重大专项课题3项、国家自然科学基金课题12项等。其研究成果获国家专利10项,国家科技进步二等奖1项。主编专著14部,参编专著31余部。荣立个人二等功1次、三等功2次。
  • 基金资助:

    国家十二五重大专项(2012ZX10002004-004)

New clinical progress in diagnosing liver disease using FibroScan

ZENG Xiang-huaSHI Dai-rongWANG Yu-ming.   

  1. Institution for Infectious Diseases,Southwest Hospital,Third Military Medical University,Chongqing 400038,China
  • Online:2014-12-01 Published:2014-12-19

摘要:

FibroScan(FS)系通过测量肝脏弹性硬度情况间接反映病变进展程度,在肝纤维化、肝硬化以及肝癌等各种慢性肝病(尤其是肝纤维化与肝硬化)中表现出了良好的评估价值。为提高诊断准确度,排除肥胖腹水等影响FS结果的因素,血清学指标及其与FS的联合检测为无创诊断慢性肝病提供了新的发展方向。本文拟就FS在临床诊断肝病应用中的新进展作一介绍。

关键词: FibroScan, 肝脏硬度值, 血清学指标, 肝脏疾病, 无创

Abstract:

Abstract:FibroScan(FS),estimating the progress of liver diseases based on the measurement of liver stiffness,has been well applied to detecting various liver diseases including hepatitis,fibrosis,cirrhosis and carcinoma(especially for fibrosis and cirrhosis).However,considering the confounding factors such as ascites and abdominal distension,new approaches using combination of FS and serum markers have been proposed in order to increase the assessed value.And perhaps this will be the new direction of non-invasive methods in diagnosing chronic liver diseases.This review is aimed at discussing the new clinical progress of diagnosing the liver diseases by FS.

Key words: FibroScan, liver stiffness measurement, serum markers, liver disease, non-invasive

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