Abstract: Despite significant advances in comprehensive and sequential therapy，the overall five-year survival rate for carcinoma of the floor of the mouth does not improve substantially. Surgery remains the primary treatment for cancers of the floor of the mouth. The operation can be used when the lesion is small and superficially infiltrated. A much more satisfactory approach is to expose the floor of the mouth by the mandibular lip-split surgery when locally advanced carcinoma of the floor of mouth is surgically managed，but there often are some complications. The pull-through technique can be used to preserve the mandible and masticatory function for selective patients with floor-of-mouth cancers. As a radical resection of primary tongue/floor-of-mouth cancer，the compartmental surgery has shown its scientific nature and feasibility with increased local and regional controls. Marginal mandibulectomy or modified resection may improve the postoperative quality of life of patients with floor- of-mouth cancers which may minimally erode the mandible without gross invasion.

Key words: carcinoma of the floor of mouth, surgical approach, mandibular lip-split surgery, pull-through technique, compartmental surgery

摘要： 尽管口底癌的综合序列治疗方面取得了明显的进步，但患者的5年生存率并无实质性提高，手术仍然是该病主要的治疗方式。较小的早期病变可直接手术切除。下颌-唇劈开术是局部晚期口底癌的常用手术径路，术野暴露充分，然而可能会出现一些并发症。拉通术有助于保存口底癌患者的下颌骨和咀嚼功能。间室切除作为舌/口底癌原发灶根治切除的一种术式，具有科学性和可行性，可改善肿瘤的局部控制率。而对于下颌骨有浅层侵犯的口底癌，则可采用边缘性下颌骨切除术或改良下颌骨切除术，以提高患者术后生存质量。

关键词: 口底癌, 手术治疗, 下颌-唇劈开术, 拉通术, 间室外科