Abstract: Objective　To observe the clinical effects and color stability of early caries lesions treated with resin infiltration. Methods　According to the inclusion/ exclusion criteria，and there were 10 patients （27 teeth） with early caries lesions were treated with resin infiltration. The results were classified into three levels：effective，partially effective，and unchanged. Standardized digital photographs of the patients were taken before treatment，and immediately，6 and 12 months after treatment，respectively. Pictures were analyzed using the Image J software. The area of white spot （W） and whole tooth labial surface （L） were measured，and then we analyzed the ratio of W/L. A nonparametric Wilcoxon rank test was used to do the statistical analysis，and P < 0.05 was considered statistically significant. Results　Among the 27 teeth，8 teeth （29.6%） were evaluated as effective，19 teeth （70.4%） were evaluated as partial effective，and no tooth was evaluated unchanged. The mean value of the W/L decreased from 28.71% to 4.34% after resin infiltration treatment （by nonparametric Wilcoxon rank test，P < 0.05）. After the 6 and 12 months follow-up，we didn’t observe the color change or the caries enlarged through the examination. Conclusion　The clinical effect of early caries lesions treated with resin infiltration is significant. During 12 months of follow-up，the clinical effect keeps stable and no further demineralization is observed. Therefore，resin infiltration can be used as a novel choice for minimally invasive treatment for early caries lesions.

Key words: early caries lesions, resin infiltration, minimally invasive treatment

摘要： 目的　观察树脂渗透技术治疗前牙唇面早期龋的临床效果及稳定性。方法　根据纳入与排除标准，对10例患者的27颗前牙唇面早期龋白垩斑进行树脂渗透治疗。临床治疗效果分为3级：有效、部分有效、无效。患者于术前及术后即刻、6个月、12个月进行检查，均在同一标准下拍摄口内像，采用Image J测量术前、术后即刻白垩斑面积（the area of white spot，W）及患牙唇面面积（the area of labial surface，L），计算W/L的值，即白垩斑面积所占比。采用两样本非参数Wilcoxon秩和检验进行统计学分析，P < 0.05为差异具有统计学意义。结果　27颗患牙的临床治疗效果：8颗（29.6%）为有效，19颗（70.4%）为部分有效，0颗为无效。部分有效的患牙术前W/L平均值是28.71%，术后即刻降至4.34%，经两样本非参数Wilcoxon秩和检验，P < 0.05。术后6、12个月复查，通过视诊和探诊未见有龋洞形成，未见牙面变色与着色。结论　树脂渗透技术治疗早期龋的临床效果确切，在12个月观察期内效果保持稳定，未见继续脱矿发展形成龋洞，可以作为早期龋微创治疗的新选择。

关键词: 早期龋, 渗透树脂, 微创治疗