Abstract:

Mineralized collagen is a new effective bone substitute composed of collagen and hydroxyapatite. It is synthesized by in vitro bionics，and simulates natural bone. The qualitative chemical composition and structure is a porous material with a strict three-dimensional hierarchical sequence. Because of its good mechanical properties，biocompatibility，osteoconductivity，osteoinductivity and biodegradability，it is widely used as a repair material in stomatology. This paper reviews the structural composition，properties，classification and oral clinical application of mineralized collagen，aiming to lay the foundation for future scientific use.

Key words: mineralized collagen, biological characteristics, bone regeneration, oral clinical application

摘要：

矿化胶原材料是由胶原和羟基磷灰石组成的新型、有效的骨替代材料，多通过体外仿生学方法合成，模拟天然骨质的化学组成和结构，是一种严格的三维等级序列的多孔材料。因其具有良好的机械性能、生物相容性、骨传导性、骨诱导性和生物降解性等特性，在口腔医学中作为修复材料被广泛应用。文章就矿化胶原材料的性质、分类及其在口腔临床中的应用做一综述，以期为以后科学使用该种材料奠定基础。

关键词: 矿化胶原, 生物学特性, 骨再生, 口腔临床应用