Abstract:

Platelet-rich fibrin（PRF），the second generation of platelet concentrate，is defined as an autologous leukocyte- and platelet-rich fibrin biomaterial. High quantities of growth factors in PRF provide biological environment for mesenchymal stem cells to participate in tissue regeneration，and the fibrin in PRF is used as a biological scaffold. This article summaries the research progress on platelet-rich fibrin in oral tissue regeneration.

Key words: platelet-rich fibrin, PRF；stem cells；oral tissue regeneration

摘要：

富血小板纤维蛋白（platelet-rich fibrin，PRF）是自体来源的富含白细胞、血小板的纤维蛋白生物材料，为第二代血小板浓缩物。PRF中含有多种生长因子，可为参与组织再生的间充质干细胞提供生物性的生长环境；此外，其纤维成分也可起到生物支架作用。文章对PRF应用于口腔组织再生的研究进展做一综述。

关键词: 富血小板纤维蛋白, 干细胞, 口腔组织再生