Acta Metallurgica Sinica

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Research progress of photodynamic therapy applied to root canal disinfection.

LIU Shi-daZHU Ya-qin   

  1. Department of General Dentistry,Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai Key Laboratory of Stomatology,Shanghai 200011,China
  • Online:2014-04-15 Published:2014-04-28

光动力疗法应用于根管消毒研究进展

刘事达综述朱亚琴审校   

  1. 作者单位:上海交通大学医学院附属第九人民医院口腔综合科,上海市口腔医学重点实验室,上海200011
  • 通讯作者: 朱亚琴
  • 基金资助:

    上海市科学技术委员会项目(08JC1414500);上海市教委科研创新重点项目(09ZZ116)

Abstract:

Abstract:As a safe and effective strategy of root canal disinfection,photodynamic therapy mainly relies on the reactive oxygen species generated by excited photosensitizer to kill cells of bacteria. The antibacterial efficacy of photodynamic therapy is affected by many variables and parameters,while the antibiofilm efficacy of it remains to be improved.

Key words: photodynamic therapy, photosensitizer, reactive oxygen species, biofilms

摘要:

光动力疗法主要依靠光敏剂活化产生的活性氧来杀伤细菌细胞,可作为一种安全、有效的消毒方法应用于根管治疗。光动力疗法的杀菌效果受到光敏剂及其浓度、光源与照射参数、暗处理时间、光纤的使用、细菌的种类与状态、组织抑制因子等多方面影响。而光动力疗法对细菌生物膜的消毒效果也有望得到提高。

关键词: 光动力疗法, 光敏剂, 活性氧, 细菌生物膜

CLC Number: