关键词: 不可复性牙髓炎, 心血管疾病, 焦虑, 疼痛, 局部麻醉 

Abstract: The pulp of irreversible pulpitis is in a state of inflammation and infection，which may lead to the failure of local anesthesia before pulp treatment and pain control during treatment to achieve the desired effect，and patients often have subjective feelings of tension and anxiety at this time. At the same time，anxiety and pain will seriously affect the treatment of patients with irreversible pulpitis combined with cardiovascular diseases，which may lead to cardiovascular and cerebrovascular accidents，and acute myocardial infarction or even death and other adverse consequences in serious cases in the treatment process. Therefore，pulp treatment with irreversible pulpitis and cardiovascular disease requires special attention to pain management，anxiety relief and the correct use of local anesthetics. This article reviews the research progress in the assessment and control methods of anxiety and pain in patients with cardiovascular disease before and during the treatment of irreversible pulpitis and analyzes the interaction between local anesthesia and cardiovascular drugs，in order to improve the safety of clinical diagnosis and treatment.

Key words: irreversible pulpitis, cardiovascular disease, anxiety, pain, local anesthesia