中国实用口腔科杂志

中国实用口腔科杂志

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类风湿关节炎与慢性牙周炎关系研究

王绍峰1a，刘海杰1a，赵欣欣1b，崔有晨1a，毕莹1b，苗培洋2   

  1. 1. 中国医科大学附属第四医院a口腔科，b风湿免疫科，辽宁  沈阳  110032；2. 法库县中心医院口腔科，辽宁  沈阳  110400
  • 出版日期:2016-10-15 发布日期:2016-12-15
  • 基金资助:

    辽宁省教育厅科学研究一般项目（L2013288）

  • Online:2016-10-15 Published:2016-12-15

摘要：

目的    探讨类风湿关节炎（rheumatoid arthritis，RA）与慢性牙周炎（chronic periodontitis，CP）之间的关系。方法    选择2014年1月至2015年1月于中国医科大学附属第四医院风湿免疫科确诊为RA的患者30例（RA组）和同期于中国医科大学附属第四医院体检中心进行常规体检者23例（对照组），两组在性别及年龄上相匹配。检测两组患者的菌斑指数（plaque index，PLI）、出血指数（bleeding index，BI）、探诊深度（probing depth，PD）、附着丧失（attachment loss，AL）、缺失牙数等牙周指标，比较两组患者牙周状况、CP患病率及中、重度牙周炎的分布情况。结果    RA组患者PLI、AL、缺失牙数、CP患病率及中、重度牙周炎比例均高于对照组（均P < 0.05），而两组BI、PD的差异无统计学意义（P > 0.05）。结论    RA患者比正常人群的牙周状况差，且其患中、重度牙周炎的比例要高于正常人群。

关键词: 类风湿关节炎, 慢性牙周炎, 附着丧失

Abstract:

Objective    To investigate the relationship between rheumatoid arthritis（RA）and chronic periodontitis（CP）. Methods    Totally 30 patients with RA（as the RA group）from January 2014 to January 2015 were compared with 23 matched healthy controls（as the control group）. Periodontal status including plaque index（PLI），bleeding index（BI），probing depth（PD），attachment loss（AL）and missing teeth was examined. Prevalence of CP and the distribution of moderate periodontitis and severe periodontitis were analyzed between two groups. Results    Prevalence of CP was higher in the RA group than in the control group（P < 0.05）. More cases of moderate periodontitis and severe periodontitis were found in the RA group compared with the control group（P < 0.05）and the RA patients had a greater number of missing teeth（P < 0.05）. There were statistical differences in AL and PLI between the two groups（P < 0.05），but BI and PD had no statistical differences（P > 0.05）. Conclusion    Periodontal condition of the RA patients is worse than that of healthy persons，and the proportion of patients with moderate and severe periodontitis is higher in the RA patients than in the healthy persons.

Key words: rheumatoid arthritis, chronic periodontitis, attachment loss