中国实用儿科杂志

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自身炎症性疾病临床诊断

宋红梅李冀   

  1. 作者单位:中国医学科学院 北京协和医院儿科,北京 100730
  • 出版日期:2015-01-06 发布日期:2014-12-31
  • 基金资助:

    2014年度公益性行业科研专项(201402012)

Clinical diagnosis of autoinflammatory disease.

SONG Hong-meiLI Ji.   

  1. Department of Pediatrics of Peking Union Medical College Hospital,Chinese Academy of Medical Sciences, Beijing 100730, China
  • Online:2015-01-06 Published:2014-12-31

摘要:

自身炎症性疾病(autoinflammatory diseases or disorders,AIDs)是一组以反复发热、急性关节炎和急性期蛋白增加为特征的复发性非侵袭性炎症性疾病。以往由于认识不足以及缺乏诊断条件,对这类疾病估计不足。随着基因诊断技术的进步、炎症发生发展机制与信号通路研究的日益进展,近年来对自身炎症性疾病的研究有了飞速进展,这也对临床诊断提出了更新的挑战。

关键词: 自身炎症性疾病, 临床诊断, 中条-西村综合征, 自身炎症性骨病

Abstract:

Abstract: Autoinflammatory diseases or disorders (AIDs) are a group of recurrent non-invasive inflammatory diseases characterized by fever, acute arthritis and elevated acute-phase proteins. The disease was underestimated in large part during the past few years due to insufficient understanding and lack of means of diagnosis. With the increasing advance of genetic diagnosis technology and of research on the mechanism of the inflammatory occurrence and the development and the signal pathway, study about the AIDs has made a rapid progress, which also proposed the new challenge to immunological pediatrician for clinical practice.

Key words: autoinflammatory diseases/disorders, clinical diagnosis, Nakajo-Nishimura syndrome, autoinflammatory bone disease

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