中国实用儿科杂志

中国实用儿科杂志

• 专题笔谈 •    下一篇

孕期疫苗接种

  

  1. 国家儿童医学中心，首都医科大学附属北京儿童医院，北京市儿科研究所，儿科学国家重点学科，国家呼吸系统疾病临床医学研究中心，教育部儿科重大疾病研究重点实验室，儿童呼吸道感染性疾病研究北京市重点实验室，北京  100020
  • 出版日期:2018-06-06 发布日期:2018-06-11

Vaccination during pregnancy

  1. Key Laboratory of Major Diseases in Children and National Key Discipline of Pediatrics（Ministry of Education）；National Clinical Research Center for Respiratory Diseases；Beijing Key Laboratory of Pediatric Respiratory Infection Diseases；Beijing Pediatric Research Institute；Beijing Children’s Hospital，Capital Medical University，Beijing  100045，China
  • Online:2018-06-06 Published:2018-06-11

摘要：

孕期接种疫苗可保护孕妇、胎儿及新生儿免受疫苗可预防疾病的危害。母体中的免疫球蛋白Ｇ（IgG）可经主动转运通过胎盘屏障，为胎儿和婴幼儿提供被动免疫保护。目前，推荐孕期可接种的疫苗包括破伤风类毒素疫苗、无细胞百日咳疫苗和灭活流感疫苗，不推荐接种活病毒疫苗。孕期接种肺炎链球菌疫苗、脑膜炎球菌疫苗、B族链球菌疫苗、肝炎疫苗和脊髓灰质炎疫苗的安全性和有效性研究已经起步，未来可通过孕妇免疫接种预防更多感染性疾病。

关键词: 孕妇, 免疫接种, 安全性, 有效性

Abstract:

Maternal immunization can protect the pregnant woman，fetus，and the neonates from vaccine-preventable infections. Maternal immunoglobulin G is actively transported across the placenta，providing passive immunity for the fetus and the infant. Currently，the tetanus toxoid，acellular pertussis vaccine，and the inactivated influenza vaccine are recommended in pregnancy. Live-virus vaccines are not recommended for the women in pregnancy. The safety and efficacy of several other vaccines including pneumococcus，meningococcus，group B streptococcus，hepatitis，and poliovirus are under research. More infection will be prevented by vaccination during pregnancy in the future.

Key words: pregnant women, immunization, safety, efficacy