中国实用儿科杂志

中国实用儿科杂志

• 专题笔谈 • 上一篇    下一篇

振幅整合脑电图在新生儿重症监护病房的应用

  

  1. 浙江大学医学院附属儿童医院NICU, 浙江  杭州  310052
  • 出版日期:2017-05-06 发布日期:2017-05-10

Application of amplitude-integrated EEG in neonatal ICU

  1. Children’s Hospital，Zhejiang University School of Medicine，Hangzhou  310052，China
  • Online:2017-05-06 Published:2017-05-10

摘要：

振幅整合脑电图（aEEG）是将源于单通道（P3-P4）或双通道（C3-P3、 C4-P4）等有限数量导联的原始脑电图经过过滤、 校正和时间压缩形成基于振幅为主要元素的脑电活动趋势。因其具有可实时、 连续、 无创床旁监测脑电活动以及相对易判读和操作等特点被广泛应用于国内外新生儿重症监护病房。aEEG在评估脑电活动背景、诊断癫痫并监测抗癫痫药物疗效、预测和评估早产或足月儿神经系统预后等具有重要的临床价值。随着技术更新， 目前还可进行多导联aEEG记录， 且同时跟踪原始脑电图， 使得aEEG对脑电背景活动的评估以及癫痫发作的诊断更具有可靠性。

关键词: 振幅整合脑电图, 新生儿, 重症监护病房

Abstract:

Amplitude integrated EEG（aEEG）is derived from limited channels （usually P3-P4 or C3-P3，C4-P4） and is filtered，rectified and time-compressed to serve as a real-time，noninvasive，bedside cerebral function monitoring. It’s simple application and interpretation has resulted in increasing use in neonatal intensive care units across the world. Current evidence demonstrates that aEEG is useful to monitor cerebral background activity，diagnose and treat seizures and predict neurodevelopmental outcomes for preterm and term infants.  Validation investigation with full array EEG have shown reliable results in interpretation of cerebral electric background and electrographic seizures，especially when used with the simultaneously displayed raw EEG trace.

Key words: amplitude integrated EEG, neonate, intensive care units