关键词: 重症急性胰腺炎, 多因素评分, 床旁急性胰腺炎严重度指数评分, C反应蛋白, 降钙素原

Abstract: Evaluation method and clinical significance of early severity of severe acute pancreatitis        WANG Zheng, ZHAO Shuo, WU Zheng, et al. Department of Hepatobiliary Surgery, Department of Pancreas Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China 
Corresponding author: XU Ke-dong, E-mail: yi89yi@xjtu.edu.cn
Abstract    Severe acute pancreatitis (SAP) is a severe pancreatic inflammation with acute onset and intense abdominal pain, accompanied by severe local and systemic complications, which could lead to high mortality. Previous studies have shown that the first 24 hours after the onset of acute pancreatitis is critical for identifying SAP patients and intensifying targeted treatments, to reduce the incidence of complications and mortality. Moreover, accurately identifying mild acute pancreatitis cases is equally critical to avoid overtreatment and extra financial burden for patients. According to both domestic and international research, as well as the experience of our center, the author analyzed numerous multifactorial scoring systems and biochemical markers for predicting severity and recommended to use of the BISAP score combined with C-reactive protein and procalcitonin as the primary predictive factors and markers to predict the severity of acute pancreatitis. However, given SAP's complex pathological process, rapid progression, and numerous influencing factors, further in-depth research is essential for a faster and more accurate prediction of SAP.

Key words: severe acute pancreatitis, multiple factorial scoring system, BISAP score, C-reactive protein, procalcitonin