中国实用外科杂志

中国实用外科杂志

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抗凝药物治疗静脉血栓栓塞症争议与共识

张福先1，侯本新2，吴勇金2   

  1. 1首都医科大学附属北京世纪坛医院血管外科，北京100038；2海南省第三人民医院，海南三亚572000
  • 出版日期:2021-12-01

  • Online:2021-12-01

摘要： 静脉血栓栓塞症（VTE）包括深静脉血栓形成（DVT）和肺动脉栓塞（PE），是同一疾病在不同阶段和身体不同部位的两种表现形式。VTE是仅次于心脏病和中风后的第三大常见心血管疾病死亡原因。美国每年＞900 000例病人发生症状性VTE，除带来巨大的医疗负担外，其中300 000例病人死于PE。1949年，抗凝被作为首选治疗方法引入我国后，至今仍占据VTE一线治疗地位。然而，虽然到目前为止我国已经在VTE的诊治中积累了丰富经验，但依然存在一些问题尚待研究和解决。

关键词: 静脉血栓栓塞症, 深静脉血栓, 肺动脉栓塞, 抗凝治疗

Abstract: Controversy and consensus on the treatment of venous thromboembolism with anticoagulant drugs        ZHANG Fu-xian*, HOU Ben-xin, WU Yong-jin. *Department of Vascular Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing100038, China
Corresponding author：ZHANG Fu-xian，E-mail:fuxain@263.net
Abstract    Venous thromboembolism（VTE），including of deep vein thrombosis（DVT）and pulmonary embolism（PE），are two manifestations of the same disease in different stages and different parts of the body. VTE in the third most common cause of cardiovascular death after heart attack and stroke.VTE is responsible for the hospitalization of at least 900，000 Americans annually and represents a significant healthcare burden with 300，000 of them died in PE. In 1949，anticoagulation was first introduced as the preferred treatment of VTE and remained the first-line treatment for VTE today.However，although we have so far accumulated rich experience in the diagnosis and treatment of VTE，there are still some problems that need to be further studied and resolved. 

Key words: venous thromboembolism, deep vein thrombosis, pulmonary embolism, anticoagulant therapy