关键词: 肝细胞癌, 肝动脉灌注化疗, 转化治疗

Abstract: The role of hepatic arterial infusion chemotherapy in conversion therapy for hepatocellular carcinoma        XU Li, CHEN Min-shan, HU Zi-li. Department of Liver Surgery, Sun Yat-sen University Cancer Center；State Key Laboratory of Oncology in Southern China；Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060，China
Corresponding author：CHEN Min-shan, E-mail:chenmsh@sysucc.org.cn
Abstract    Radical resection is the main treatment for patients with hepatocellular carcinoma（HCC）who got long term survival. However Chinese patients with HCC are often diagnosed at intermediate-advanced stage，and less than 30% of them could receive radical resection. Numerous efforts have been made to shrink or down-staging HCC in order to create the chances for radical resection. In recent years，hepatic arterial infusion chemotherapy（HAIC）with oxaliplatin/CF/5-FU（FOLFOX regimen）has showed significant superiority in tumor response rate and safety，and created better chances for radical resection of HCC as a conversion therapy. Combined treatments with FOLFOX-HAIC play more and more important roles in HCC therapy.

Key words: hepatocellular carcinoma, hepatic arterial infusion chemotherapy, conversion therapy