关键词: 肝内胆管癌, 淋巴结转移, 淋巴结清扫, 预后

Abstract: Characteristics of lymph node metastasis and prognostic significance of lymphadenectomy in intrahepatic cholangiocarcinoma        ZHOU Wei-ping, JIANG Bei-ge.The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Military Medical University, Shanghai 200438, China
Corresponding author: ZHOU Wei-ping, E-mail：ehphwp@126.com
Abstract    Intrahepatic cholangiocarcinoma（ICC）is a sort of bile duct epithelium malignant tumor originating from the intrahepatic interlobular bile duct to the secondary bile duct，accounting for 10% of the bile duct malignant tumors. Radical surgical resection remains the only hope for cure patients with ICC. Lymph node metastasis is the most important prognostic independent risk factor for ICC. There are obvious controversies on whether lymphadenectomy should be performed or the specific area of dissection for patients with ICC for radical resection.Current guidelines suggest that regional lymphadenectomy is a standard part of surgical management for surgically resectable ICC patients，providing decisions for accurate postoperative staging and selection patients for further adjuvant therapy. All ICC patients with lymph node metastasis should receive postoperative systematic treatment.However，some studies indicate that surgical resection for patients with LN-positive ICC may not improve survival compared to chemotherapy alone.

Key words: intrahepatic cholangiocarcinoma, lymph node metastasis, lymphadenectomy, prognosis