中国实用外科杂志

• 普通外科进展(2000-2020) • 上一篇    下一篇

结直肠癌外科临床研究进展及展望

张忠涛杨盈赤   

  1. 首都医科大学附属北京友谊医院普外科 国家消化系统疾病临床研究中心普外分中心,北京 100050
  • 出版日期:2020-01-01 发布日期:2020-01-16

  • Online:2020-01-01 Published:2020-01-16

摘要: 进入21世纪以来,普通外科学发展迅速,理念不断更新,新技术不断涌现,这在结直肠癌治疗领域表现更加具有代表性和特色。尽管手术作为结直肠癌治疗的核心已经相当成熟,但外科领域开展随机对照研究难度很大,很多新的治疗方法和技术的优效性需要一个漫长的证明过程,而规范和科学的开展结直肠癌外科临床研究可能是解决这一问题的根本方法。总结目前结直肠外科的几个热点问题相关临床研究的新进展,结果可以看出,将最大限度地保留功能、获得更好的生活质量与延长生存时间更好的结合在一起是未来结直肠癌外科治疗的目标,而通过开展相应的临床研究,获得更多的循证医学证据,在此基础上让结直肠癌的外科治疗更加规范,是实现这一目标的必由之路。

关键词: 结直肠癌, 临床研究, 经肛全直肠系膜切除, 侧方淋巴结清扫, 新辅助治疗, 机器人手术

Abstract: Advances and prospects in clinical research of colorectal cancer surgery        ZHANG Zhong-tao,YANG Ying-chi. Department of General Surgery,National Clinical Research Center for Digestive Diseases,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China
Corresponding author: ZHANG Zhong-tao,E-mail:zhangzht@
ccmu.edu.cn
Abstract    Since the beginning of the 21st century,the general surgery has developed rapidly,with the constantly updating ideas and new technologies,and it has become more representative in the treatment of colorectal cancer. However,it is very difficult to perform randomized controlled study in the surgical field,and the provement of the effectiveness for new treatments and technologies need a long process,the standardized and scientific clinical research might be the fundamental method to solve this problem. This paper summarizes the new progress of clinical research on several hot issues related to colorectal surgery. It can be seen that the future goal is to maximize the retention of function,obtain a better quality of life and prolong the survival time. Therefore,the only way to achieve this goal is to obtain more clinical researches and evidence-based standardized surgical treatment in colorectal cancer.

Key words: colorectal cancer, clinical research, taTME, lateral lymph node dissection, neoadjuvant treatment, robotic surgery