关键词: 胰腺神经内分泌肿瘤, 根治性切除, 淋巴结清扫, 预后

Abstract:

Value and controversy of lymphadenectomy for pancreatic neuroendocrine neoplasms        GUO Shi-wei，JIN Gang. Department of Hepato-Biliary-Pancreatic Surgery，Changhai Hospital，Navy Medical University，Shanghai 200433，China
Corresponding author：JIN Gang．E-mail：jingang@smmu.edu.cn
Abstract    In recent years，with the progress of imaging and diagnostic technology，the detection rate of pancreatic neuroendocrine neoplasms has increased rapidly. However，its clinical manifestations are diverse，the rate of misdiagnosis is high，the therapeutic treatments are complex，and the guidelines for diagnosis and treatment are relatively imperfect，which has caused great trouble in clinical practice. Especially in surgical treatment，it is difficult to choose between preservation of pancreatic function and standard radical resection，especially for tumors less than 2 cm. At the same time，whether lymph node resection should be performed is another open question. Because it is difficult to carry out randomized controlled studies，most of the studies on this issue are long-span retrospective studies based on public databases，which are greatly influenced by factors such as time，medical level in different regions and different surgeons. It is the confounding factors that lead to inconsistent results.

Key words: pancreatic neuroendocrine neoplasms, radical resection, lymphadenectomy, prognosis