中国实用外科杂志

中国实用外科杂志

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腹腔感染继发器官功能障碍病人预后分析

董妍妍1，2，崔瑞霞1，苗润晨1，王    铮1，张靖垚1，刘    昌1a   

  1. 1西安交通大学第一附属医院 a.肝胆外科  b.SICU，陕西西安 710061；2西安交通大学医学部护理学系，陕西西安 710061
  • 出版日期:2019-06-01 发布日期:2019-06-12

  • Online:2019-06-01 Published:2019-06-12

摘要：

目的    分析腹腔感染继发器官功能障碍病人临床特点及其预后。方法    回顾性分析2014年1月至2017年12月西安交通大学第一附属医院收治的606例腹腔感染继发器官功能障碍的病人临床资料，收集人口学资料、治疗及结局等数据。分析腹腔感染继发器官功能障碍的发生率、病死率、治疗及预后危险因素。结果    腹腔感染继发器官功能障碍的发生率和病死率分别为40.6%和14.7%。病死率随着器官功能障碍的器官数量的增加而升高。预后的单因素分析结果显示，器官功能障碍数量、原发感染部位、连续性肾脏替代治疗（CRRT）、人工肝支持、有无合并症、急性生理与慢性健康状况评分（APACHEⅡ评分）、序贯性器官功能衰竭评分（SOFA评分）等因素均影响腹腔感染继发器官功能障碍病人的预后。多因素分析显示，器官功能障碍数量、人工肝支持、APACHEⅡ评分、SOFA评分是影响腹腔感染继发器官功能障碍病人预后的危险因素。结论    腹腔感染继发器官功能障碍的发生率、病死率均较高。器官功能障碍数量、人工肝支持、APACHEⅡ评分、SOFA评分是影响腹腔感染继发器官功能障碍病人预后的危险因素。

关键词: 腹腔感染, 器官功能障碍, 临床特点, 预后

Abstract:

Prognosis of patients with secondary organ dysfunction caused by intra-abdominal infections        DONG Yan-yan*, CUI Rui-xia, MIAO Run-chen, et al. *Department of Hepatobiliary Surgery, Department of SICU, the First Affiliated Hospital of Xi’an Jiaotong University; Department of Nursing, School of Medicine, Xi’an Jiao-tong University, Xi’an 710061, China
Correspondingauthor：LIU Chang，E-mail：liuchangdoctor@163.com
Abstract    Objective    To analyze the clinical characteristics and prognosis of patients with organ dysfunction secondary to intra-abdominal infections (IAIs). Methods  606 patients with organ dysfunction secondary to IAIs who admitted to the First Affiliated Hospital of Xi’an Jiaotong University from January 2014 to December 2017 were recruited for retrospective analysis. Demographic，treatment and outcome data of all patients were collected. Incidence，mortality, treatment and risk factors were adopted for reveal the prevalence of organ dysfunction secondary to IAIs.Results The morbidity and mortality of patients with organ dysfunction secondary to IAIs were 40.6% and 14.7%，respectively. The mortality rate increased with the number of dysfunctional organs. The univariate analysis results indicated that the number of dysfunctional organs，location of primary infection，continuous renal replacement therapy (CRRT) treatment, artificial liver support, presence of comorbidities, acute physiology and chronic health status (APACHEII) score, sequential organ failure (SOFA) score were associated with the prognosis. The multivariate analysis results showed that the number of dysfunctional organs，artificial liver support，APACHEⅡscore and SOFA score were risk factors for the prognosis of patients with organ dysfunction secondary to IAIs. Conclusion  The morbidity and mortality of organ dysfunction in IAIs were high. The number of dysfunctional organs，artificial liver support，APACHEⅡscore and SOFA score were risk factors for the prognosis of patients with organ dysfunction secondary to IAIs.

Key words: intra-abdominal infections, organ dysfunction, clinical characteristics, prognosis