关键词: 乳腺癌, 保乳手术, 前哨淋巴结活检, 乳房重建, 乳腺癌分子分型

Abstract:

Strategy and progress of surgical treatment for breast cancer        CHEN Sheng, SHAO Zhi-min. Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai200032, China
Corresponding author: SHAO Zhi-min, E-mail: 0456177@fudan.edu.cn
Abstract    Nowadays, the surgical treatment of breast cancer is based on a more conservative and individualized strategy. Standard breast conservation therapy needs to be promoted further, while the positive margin, recurrence and radiotherapy are key concerning issues influencing the choice of conservation surgery for patients and surgeons. Sentinel lymph node biopsy is the standard treatment strategy for lymph node negative breast cancer. The operation technique and indication of axillary nodes dissection are still controversial. The reconstruction surgery has provided opportunities for rebuilt of breast for patients who are not candidates for conservation therapy with consideration of both aesthetics and anti-cancer treatment efficacy. The cross link of imaging technique and surgery tends to be plural, and has achieved a great progress in the biopsy and minimally invasive treatment area. The biological subtype of breast cancer has played an important role in determining intrinsic property and treatment strategy for breast cancer，especially in neoadjuvant therapy. 

Key words: breast cancer, breast conservation surgery, sentinel lymph node biopsy, breast reconstruction, breast cancer biological subtype