中国实用外科杂志 ›› 2011, Vol. 31 ›› Issue (04): 290-292.

• 专题笔谈 • 上一篇    下一篇

局部复发直肠癌综合治疗的时机及合理选择

刘云鹏,李贺明   

  1. 中国医科大学附属第一医院肿瘤内科,辽宁沈阳110001
  • 出版日期:2011-04-01 发布日期:2011-05-30

  • Online:2011-04-01 Published:2011-05-30

摘要:

随着原发性直肠癌治疗手段的不断改进,尤其是全直肠系膜切除和新辅助治疗的出现,直肠癌局部复发率显著降低。但由于受到病人曾经接受过的相关治疗的限制,局部复发直肠癌(locally recurrent rectal cancer,LRRC)的治疗一直以来是备受争议的问题。手术是其主要的治疗手段,但仅有少数病人可以获得根治。因此,针对不同治疗史的病人采取合理有效的多学科综合治疗模式是LRRC治疗的重要原则,而综合治疗时机及合理选择已成为目前研究的热点。

关键词: 直肠癌, 放射治疗, 化学治疗

Abstract:

Optimal occasion and options of multimodality therapy for locally recurrent rectal cancer        LIU Yun-peng, LI He-ming. Department of Medical Oncology,the First Hospital,China Medical University,Shenyang 110001, China
Corresponding author: LIU Yun-peng, E-mail: cmuliuyunpeng@yahoo.cn
Abstract    With the evolution in the management of rectal cancer, especially for the implementation of total mesorectal excision and neoadjuvant therapy, local recurrence rate has decreased significantly. However, the optimal treatment of locally recurrent rectal cancer (LRRC) remains a difficult and controversial issue because patients have received the neoadjuvant or adjuvant therapy during the primary rectal cancer treatment. Radical resection of the recurrence offers the best chance of cure. But it should be considered only in carefully selected patients. Therefore, multimodality therapy should be the best chance under the circumstances and the optimal options of multimodality therapy have become the point now.

Key words: rectal cancer, radiotherapy, chemotherapy