关键词: 胰源性静脉高压, 胃底静脉曲张, 消化道出血, 脾切除术

Abstract:

Diagnosis and management of gastrointestinal bleeding caused by pancreatic sinistral portal hypertension        XIE Kun, XIE Xue-hai, YANG Yin-mo . Department of General Surgery, Peking University First Hospital, Beijing 100034, China
Corresponding author: YANG Yin-mo，E-mail：yangyinmo@263.net
Abstract    Pancreatic sinistral portal hypertension is a rare syndrome presented with splenomegaly, gastric varices and gastrointestinal haemorrhage, which due to a primary pancreatic diseases such as chronic pancreatitis, pancreatic tumors. The pathology arises in the pancreas and results in compression of the splenic vein, while the splenic artery blood supply is normal, which consequently result in congestive enlargement of the spleen and back pressure changes in the left portal system. Pancreatic sinistral portal hypertension should be considered in the presence of gastrointestinal bleeding with normal liver function and unexplained splenomegaly. Splenectomy can effectively control the bleeding, however treatment of pancreatic primary disease should be involved. The overall prognosis for patients with sinistral portal hypertension is clearly dependant on the primary pathology.

Key words: pancreatic sinistral portal hypertension, gastroesophageal varices, gastrointestinal bleeding, splenectomy