Abstract:Based on the recent published large-scale clinical trials,ACCF/AHA constantly updated guide for the treatment of acute coronary syndrome.Recently,ACCF/AHA STEMI (acute ST-elevation myocardial infarction) guideline was published in Circulation in 2013,of which there were many bright spots,such as the new guideline proposed first medical contact (FMC) to reperfusion treatment time,shifting emergency treatment of STEMI to pre-hospital emergency from hospital treatment,it also stressed the status of P2Y12 inhibitor (prasugrel and ticagrelor) in STEMI patients.The latest guideline provides new evidences for the treatment of STEMI.