中国实用内科杂志

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营养不良对腹膜透析预后影响及处理对策

刘文虎   

  1. 作者单位:首都医科大学肾病学系 首都医科大学附属北京友谊医院肾内科,北京 100050
  • 出版日期:2013-06-01 发布日期:2013-06-19
  • 作者简介:刘文虎,主任医师、教授、博士生导师。首都医科大学肾病学系主任、首都医科大学附属北京友谊医院肾内科主任。兼任中华医学会肾脏病学分会常务委员;《中国血液净化杂志》、《中国全科医学》、《国际移植与血液净化》等杂志常务编委,《中华肾脏病杂志》编委等职。

Effects of malnutrition on the outcomes in peritoneal dialysis patients and the treatment program.

LIU Wen-hu.   

  1. Nephrology Department of Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China
  • Online:2013-06-01 Published:2013-06-19

摘要:

蛋白质-能量营养不良(PEM)是腹膜透析(PD)患者常见的并发症,并随着透析时间的延长而升高,严重地影响着患者的生活质量、住院率及生存率。PEM可分为原发性(Ⅰ型)和继发性(Ⅱ型)两大类。导致PEM的主要因素有炎症、糖尿病、腹膜高转运及腹膜透析患者的年龄等。防止腹膜透析患者出现PEM的主要对策包括营养支持、使用氨基酸腹膜透析液、改善微炎症状态、充分透析、控制容量负荷、纠正代谢性酸中毒、保护残余肾功能等。另外自动化腹膜透析(APD)具有透析剂量大、交换次数多、腹内透析液存留时间短等特点,因而可以较好防治腹膜透析患者的PEM。

关键词: 蛋白质-能量营养不良, 腹膜透析

Abstract:

Abstract:Protein-energy malnutrition (PEM) is a common complication in peritoneal dialysis patients.The morbidity increases with the extension of the duration of dialysis.PEM seriously affect patients quality of life,hospitalization rate and mortality.The main factors leading to PEM are inflammation,diabetes,high peritoneal transporter and elder age of patients.The main countermeasures to prevent PEM in PD patients include nutritional support,use of amino acid peritoneal dialysis solution,improvement of micro-inflammatory state,adequate dialysis,better fluid volume control,correction of metabolic acidosis,and the protection of residual renal function.In addition,automated peritoneal dialysis (APD) has the advantage of delivering higher doses of dialysis,more exchanges,shorter dwelling time,and thus might be more effective in management of PEM in PD patients.

Key words: protein-energy malnutrition, peritoneal dialysis

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