中国实用口腔科杂志

中国实用口腔科杂志 ›› 2011, Vol. 4 ›› Issue (11): 679-680.

• 论著 • 上一篇    下一篇

口腔鳞状细胞癌术后复发相关因素分析

姚红磊1，梁    进2，陈    湧1，纳应坤1，骆    奇1，刘    华1     

  1. 1.云南省第二人民医院颌面外科，昆明  650021；2.云南省肿瘤医院化疗中心，昆明  650106
  • 出版日期:2011-11-15 发布日期:2022-06-29

  • Online:2011-11-15 Published:2022-06-29

摘要： 目的    分析口腔鳞状细胞癌患者术后复发的相关临床因素。方法    随机抽取云南省第二人民医院口腔科2006年4月到2009年10月收治的62例口腔鳞状细胞癌患者的临床资料进行回顾性分析，记录患者原发肿瘤大小、区域淋巴结侵犯、邻近血管侵犯、邻近神经侵犯、手术切缘状况、淋巴结清扫数目、鳞状细胞癌的病理分级、年龄、性别等相关因素，并对数据进行相关分析。结果    对62例患者进行回顾性分析后，经统计学检验，不同的原发肿瘤大小、区域淋巴结侵犯、邻近血管侵犯、邻近神经侵犯、手术切缘状况、鳞癌的病理分级、年龄、性别的肿瘤复发差异均有统计学意义（均P＜0.05）。结论    口腔鳞状细胞癌术后复发与多种因素相关，应全面综合考虑，以降低患者术后的复发风险。

关键词: 口腔鳞状细胞癌, 术后复发, 相关因素, 回顾性分析

Abstract: Object    To investigate the factors related to recurrence of oral squamous cell carcinoma after surgery. Methods    Retrospective analysis was made in 62 cases of oral squamous cell carcinoma，record the primary tumor size，the regional lymph node involvement，nearby vessel invasion and adjacent neural invasion，as well as surgical margin status，number of lymph node dissection，the grade of histological differentiation of squamous cell carcinoma and patient’s age，sex and other related factors，and statistical analysis of χ2 test was made. Results    Regional lymph node involvement in different situations，adjacent vessel invasion，adjacent nerve invasion，surgical margin status，the grade of histological differentiation of squamous cell carcinoma and patient’s age，sex etc had a significant relationship with postoperative recurrence （P < 0.05），primary tumor size and treatment of recurrent oral squamous cell carcinoma was also significantly related to postoperative recurrence in statistical analysis of χ2 test（P < 0.05）. Conclusion      Related to recurrence of oral squamous cell carcinoma is related to many factors，therefore the specific treatment will be figured out and prognosis of patients will be forecasted.

Key words: oral squamous cell carcinoma, recurrence after carcinoma surgery, related factors, retrospective analysis