中国实用口腔科杂志

中国实用口腔科杂志

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盐酸米诺环素软膏治疗牙周脓肿疗效评价

刘丽梅，邱才卿，郝言清   

  1. 烟台市口腔医院牙周科
  • 收稿日期:2009-05-04 修回日期:2009-07-10 出版日期:2009-09-15 发布日期:2009-09-15

  • Received:2009-05-04 Revised:2009-07-10 Online:2009-09-15 Published:2009-09-15

摘要： 摘要：目的 评价2%盐酸米诺环素软膏局部应用治疗牙周脓肿的临床疗效。方法 选择2005年11月至2008年12月烟台市口腔医院牙周科门诊单发的牙周脓肿患者60例。随机分为两组，每组30例。试验组使用2%盐酸米诺环素软膏，对照组使用碘甘油，比较两组治疗后1周临床各项牙周指标的变化。结果 两组治疗后各项牙周指标均低于治疗前，试验组治疗后各项牙周指标与对照组相比，差异有统计学意义（P < 0.05）;试验组治疗有效率明显高于对照组（P < 0.05）。结论 2%盐酸米诺环素软膏局部用于治疗牙周脓肿，能有效改善临床症状。

关键词: 盐酸米诺环素, 局部缓释剂, 牙周脓肿

Abstract: Abstract：Objective To study therapeutic effects of 2% minocycline paste on periodontal abscess. Methods Sixty patients suffering from periodontal abscess were randomly assigned to two groups with 30 for each from November，2005 to December，2008. The 2% minocycline paste was used in experiment group，while iodoglycerin was used in control group. The difference of PLI， EBI，PD and MD was measured and analysed between pre-medication and post-medication. Results After one week， two groups both showed significant reducation in PLI，EBI，PD and MD. Very significant difference of PLI，EBI，PD and MD was seen between experiment group and control group（P < 0.05）. Conclusion The 2% minocycline paste plays an important role in effectively improving clinical symptoms of periodontal abscess.

Key words: minocycline, local retarder, periodontal abscess