Abstract: Autoimmune thyroid disease is one of the commonest disease in pregnancy women．Several researches have found out that thyroid antibody positivity is related to miscarriage, preterm birth, infertility, placental abruption, perinatal mortality and postpartum thyroiditis．The early detection of the thyroid function and antibodies before and during pregancy is important for clinical intervention.This article summarizes the latest progress in screening and treatment of pregnancy-associated autoimmune thyroid disease, hoping to offer guidance for the clinician.