Abstract: The pathophysiology of ITP is complicated and the onset of ITP is progressing slowly. The clinical features of ITP are similar to those of the other diseases leading to thrombocytopenia, the differential diagnosis is often difficult. The treatment in the perinatal period is very important because if it is treated improperly, the mother and fetus will be endangered. In recent years, although the study of ITP has been greatly developed，and many countries have developed the guidelines and consensus on how to manage ITP , but there is still controversy about the ideal strategy of diagnosis and treatment of ITP in pregnancy. This paper focused on elaborating the clinical manifestations, the impact on the pregnant women and fetuses, diagnosis, differential diagnosis and the treatment progress of ITP in pregnancy by reviewing recent literatures.