Abstract: Antiphospholipid syndrome is the non-inflammatory autoimmune disease caused by antiphospholipid antibodies. In the pregnancy with APS, the following may occur: recurrent spontaneous abortion in the first trimester, intrauterine fetal death in the third trimester, fetal growth restriction, thrombocytopenia, preeclampsia or eclampsia, placental dysfunction and other adverse pregnancy outcome. All these will do great harm to the health of mothers and fetuses.We should pay more attention to the diagnosis and treatment of obstetric APS.