Clinical application of Kangfuyan capsule in the treatment of partially obstructed fallopian tube infertility.
ZHANG Yu,XU Guo-ping,SUN Li,SUN Xia.
Chinese Journal of Practical Gynecology and Obstetrics ›› 2015, Vol. 31 ›› Issue (7) : 672-675.
Clinical application of Kangfuyan capsule in the treatment of partially obstructed fallopian tube infertility.
Abstract: Objective To investigate therapeutic efficiency of Kangfuyan capsule on infertile patients with partially obstructed fallopian tube infertility. Methods Total 143 mild patients and 120 severe patients with partially obstructed fallopian tube were selected according to the imaging diagnosis of hysterosalpingography. Patients with mild partially obstructed fallopian tube were randomly divided into treatment group (89 cases) and control group (54 cases),and the combined therapy of hydrotubation and Kangfuyan capsule were used in treatment group,while the control group only received hydrotubation. Patients with severe partially obstructed fallopian tube were randomly divided into treatment group (77 cases) and control group (43 cases),and the combined therapy of hysteroscopy-laparoscopic surgery and Kangfuyan capsule were used in treatment group,while the control group only received hysteroscopy-laparoscopic surgery.Results The rate of intrauterine pregnancy in treatment group with mild partially obstructed fallopian tube was higher than control group(70.8% vs. 51.9%),the difference being statistically significant(P<0.05). The rate of tubal pregnancy rate was lower than control group(1.1% vs. 7.4%),the difference being statistically significant(P<0.05). There was no statistically significant difference between two groups in the rate of biochemical pregnancy (4.5% to 7.4%) (P>0.05). The intrauterine pregnancy in treatment group with severe partially obstructed fallopian tube was higher than control group(37.7% vs. 20.9%),the difference being statistically significant(P<0.05). The rate of tubal pregnancy rate was lower than control group(5.2% vs. 16.3%),the difference being statistically significant(P<0.05). There was no statistically significant difference between two groups in the rate of biochemical pregnancy (6.5% vs. 9.3%) (P>0.05). Through 12 months of follow-up, among non-pregnant patients, the rate of partially obstructed fallopian tube (26.2% vs. 50%) and completely obstructed fallopian tube(4.8% vs. 22.2%) in treatment group with mild partially obstructed fallopian tube were lower than control group, the difference being statistically significant(P<0.05);the rate of partially obstructed fallopian tube (32.1% vs. 52.2%) and completely obstructed fallopian tube(7.7% vs. 21.7%) in treatment group with severe partially obstructed fallopian tube were lower than control group, the difference being statistically significant(P<0.05).Conclusion Kangfuyan capsule has good curative effect in auxiliary treatment of partially obstructed fallopian tube,which can improve the intrauterine pregnancy and tubal recanalization rate,and reduce tubal pregnancy rate at the same time.
infertility / Kangfuyan capsule / fallopian tube / partially obstructed
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(2015-01-25 收稿 2015-03-14 修回)
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