Expression and clinical significance of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human ovarian cancers tissues.

LI Zheng-tao,FANG Yuan-yuan.

Chinese Journal of Practical Gynecology and Obstetrics ›› 2015, Vol. 31 ›› Issue (6) : 552-555.

Chinese Journal of Practical Gynecology and Obstetrics ›› 2015, Vol. 31 ›› Issue (6) : 552-555. DOI: 10.7504/fk2015050117

Expression and clinical significance of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human ovarian cancers tissues.

  • LI Zheng-tao,FANG Yuan-yuan.
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Abstract

Abstract: Objective To investigate expression and clinical significance of CIP2A in ovarian cancer tissues.

Key words

CIP2A / ovarian cancer / tumor grade

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LI Zheng-tao,FANG Yuan-yuan.. Expression and clinical significance of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human ovarian cancers tissues.[J]. Chinese Journal of Practical Gynecology and Obstetrics. 2015, 31(6): 552-555 https://doi.org/10.7504/fk2015050117

References

[1] Junttila MR,Puustinen P,Niemelä M,et al. CIP2A inhibits PP2A in human malignancies[J]. Cell,2007,130(1): 51-62.

[2] Dong QZ,Wang Y,Dong XJ,et al. CIP2A is overexpressed in non-small cell lung cancer and correlates with poor prognosis[J]. Ann Surg Oncol,2011,18(3): 857-865.

[3]  Côme C,Laine A,Chanrion M,et al.CIP2A is associated with human breast cancer aggressivity[J]. Clin Cancer Res,2009,15(16): 5092-5100.

[4] Böckelman C,Hagström J,Mäkinen LK,et al. High CIP2A immunoreactivity is an independent prognostic indicator in early-stage tongue cancer[J]. Br J Cancer,2012,104(12): 1890-1895.

[5] Guo Z,Liu D,Su Z. CIP2A mediates prostate cancer progression via the c-MYC signaling pathway[J]. Tumour Biol,2015,[Epub ahead of print]

[6] Huang J,Jia J,Tong Q,et al. Knockdown of cancerous inhibitor of protein phosphatase 2A may sensitize metastatic castration-resistant prostate cancer cells to cabazitaxel chemotherapy[J]. Tumour Biol,2015,36(3):1589-1594.

[7] Schwartz DR,Kardia SL,Shedden KA,et al. Gene expression in ovarian cancer reflects both morphology and biological behavior,distinguishing clear cell from other poor-prognosis ovarian carcinomas[J]. Cancer Res,2002,62(16): 4722-4729.

[8] Zorn KK,Bonome T,Gangi L,et al. Gene expression profiles of serous,endometrioid,and clear cell subtypes of ovarian and endometrial cancer[J]. Clin Cancer Res,2005,11(18): 6422-6430.

[9]. De P,Carlson J,Leyland-Jones B,et al. Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands[J]. Oncotarget,2014,5(13):4581-4602.

[10]    Kim A,Ueda Y,Naka T,et al. Therapeutic strategies in epithelial ovarian cancer[J]. J Exp Clin Cancer Res,2012,31: 14.

(2015-01-03收稿    2015-03-20修回)

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