Prognosis evaluation and follow-up of resistant trophoblastic neoplasia.

ZHAO Jun,XIANG Yang.

Chinese Journal of Practical Gynecology and Obstetrics ›› 2015, Vol. 31 ›› Issue (3) : 223-226.

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Chinese Journal of Practical Gynecology and Obstetrics ›› 2015, Vol. 31 ›› Issue (3) : 223-226. DOI: 10.7504/fk2015020111

Prognosis evaluation and follow-up of resistant trophoblastic neoplasia.

  • ZHAO Jun,XIANG Yang.
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Abstract

Abstract:Although most patients with gestational trophoblastic neoplasms have optimistic prognosis due to their sensitivity to the chemotherapy, approximately ten to twenty-five percent of them might develop resistance to the primary chemotherapy.The present article gives a brief introduction to evaluating the prognosis and follow-up of the resistant gestational trophoblastic neoplasms.

Key words

gestational trophoblastic neoplasms / resistant / prognosis / follow-up

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ZHAO Jun,XIANG Yang.. Prognosis evaluation and follow-up of resistant trophoblastic neoplasia.[J]. Chinese Journal of Practical Gynecology and Obstetrics. 2015, 31(3): 223-226 https://doi.org/10.7504/fk2015020111

References

[1]    向阳.宋鸿钊滋养细胞肿瘤学[M].3版.北京:人民卫生出版社,2011:301.

[2]   Lurain JR.Gestational trophoblastic disease Ⅱ: classification and management of gestational trophoblastic neoplasia[J].Am J Obstet Gynecol,2011,204(1):11-18.

[3]   Wang J, Short D, Sebire NJ,et al.Salvage chemotherapy of relapsed or high-risk gestational trophoblastic neoplasia (GTN) with paclitaxel/cisplatin alternating with paclitaxel/etoposide (TP/TE) [J].Ann Oncol,2008,19(9):1578-1583.

[4]   Feng F, Xiang Y, Li L, et al.Clinical parameters predicting therapeutic response to surgical management in patients with chemotherapy-resistant gestational trophoblastic neoplasia[J].Gynecol Oncol,2009,113(3):312-315.

[5]   Zhao J, Xiang Y,Wan XR, et al.Molecular genetic analyses of Choriocarcinoma[J].Placenta,2009,30(9):816-820.

[6]   Alifrangis C, Agarwal R, Short D,et al.EMA-CO for high-risk gestational trophoblastic neoplasia: good outcomes with induction low-dose etoposide-cisplatin and genetic analysis[J].J Clin Oncol,2013,31(2):280-286.

[7]   Kingdon SJ, Coleman RE, Ellis L,et al.Deaths from gestational trophoblastic neoplasia: any lessons to be learned? [J].J Reprod Med,2012 ,57(7-8):293-296.

[8]   Patel SM, Desai A.Management of drug resistant gestational trophoblastic neoplasia[J].J Reprod Med,2010,55(7-8):296-300.

[9]    周莹,冯凤芝,向阳,等.耐药和复发性妊娠滋养细胞肿瘤的临床病例分析[J].中华妇产科杂志,2010,45(11):804-807.

[10]    Alazzam M, Tidy J, Osborne R,et al.Chemtherapy for resistant or recurrent gestational trophoblastic neoplasia[J].Cochrane Database Syst Rev,2012,12:CD008891.doi: 10.1002/14651858.CD008891.pub2.

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