Clinical analysis of 8 cases with mirror syndrome
WANG Ma-lie,LIANG Run-cai.
Chinese Journal of Practical Gynecology and Obstetrics ›› 2014, Vol. 30 ›› Issue (5) : 369-373.
Clinical analysis of 8 cases with mirror syndrome
Abstract:Objective To approach the clinical features and treatment of mirror syndrome. Methods The clinical data including general state of mother nuclide,laboratory and ultrasound examination,gross and microscopic placental examination and outcomes of both mother and fetus in 8 cases with mirror syndrome at our hospital from August 2007 to May 2012 were analyzed retrospective. Results The clinical features of mirror syndrome include maternal edema,hypertension,proteinuria,dilution anemia,hypoproteinemia,hydrops fetalis and hydropic placenta. The severe patient would appear pleural fluid,ascites,pulmonary edema and congestive heart failure. The patient have a large proportion of postpartum hemorrhage,transfusion and being treated in the intensive care unit.Eight cases have several characteristics such as anemia and hemodilution[HB(77.3±9.10)g/L and HCT 0.246±0.029],hypopoteinemia [ALB(24.86 ± 3.10)g/L],and the hemoglobin,hamat and albumin were elevated significantly [HB(99.27±15.27) g/L,HCT 0.308±0.046,ALB(29.59 ± 3.13)g/L]after termination of pregnancy.Eight cases recovered increasingly after termination of pregnancy. Conclusion It's easy to confuse the diagnose between mirror syndrome and preeclampsia. Maternal dilution anemia is an important characteristic. Once mirror syndrome is diagnosed,the treatment should be considered including to correct hypopoteinemia,use diuretic agent,control the imput fluid and prevent postpartum hemorrhage. Termination of pregnancy is the basic treatment of mirror syndrome.
maternal edema / hydrops fetalis / placental edema / mirror syndrome
[1] Braun T,Brauer M,Fuchs I,et al.Mirror syndrome: a systematic review of fetal associated conditions,maternal presentation and perinatal outcome[J]. Fetal Diagn Ther,2010,27:191-203.
[2] Pirhonen JP,Hartgill TW. Spontaneous reversal of mirror syndrome in a twin pregnancy after a single fetal death[J]. Eur J Obstet Gynecol Reprod Biol,2004,116:106-107.
[3] Graham N,Garrod A,Bullen P,et al. Placental expression of anti-angiogenic proteins in mirror syndrome:A case report[J].Placenta,2012,33(6):528-531.
[4] Prefumo F,Pagani G,Fratelli N,et al. Increased concentrations of antiangiogenic factors in mirror syndrome complicating twin-to-twin transfusion syndrome[J].Prenat Diagn,2010,30(4):378-379.
[5] Llurba E,Marsal G,Sanchez O,et al. Angiogenic and antiangiogenic factors before and after resolution of maternal mirror syndrome[J].Ultrasound Obstet Gynecol,2012,40:367-369.
[6] Bixel K, Silasi M.Placental origins of angiogenic dysfunction in mirror syndrome[J].Hypertension in Pregnancy,2012,31(2):211-217.
[7] Sanchez M,Palacio M,Borrell A,et al. Prenatal diagnosis and management of fetal xerocytos is associated with asites[J]. Fetal Diagn Ther,2005,20:402-405.
[8] Lobato G,Nakamura-Pereira M. Reversion of the Ballantyne syndrome despite fetal hydrops persistence[J].Fetal Diagn Ther,2008,24(4):474-477.
[9] Garcia-Diaz L,Carreto P,Costa-Pereira S,et al. Prenatal management and perinatal outcome in giant placental chorioangioma complicated with hydrops fetalis,fetal anemia and maternal mirror syndrome[J].BMC Pregnancy Childbirth,2012,12:72.
[10] McCann SM,Emery SP,Vallejo MC,et al. Anesthetic management of a parturient with fetal sacrococcygeal teratoma and mirror syndrome complicated by elevated HCG and subsequent hyperthyroidism[J].J Clin Anesth,2009,21(7):521-524.
/
| 〈 |
|
〉 |