Clinical characteristics and pregnancy outcomes of patients with adnexal torsion during pregnancy: A single-center retrospective study

LI Meng-hui, ZHANG Zhi-qiang, LI Hua, LU Jun-li, MU Bo-ran

Chinese Journal of Practical Gynecology and Obstetrics ›› 2026, Vol. 42 ›› Issue (6) : 651-657.

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Chinese Journal of Practical Gynecology and Obstetrics ›› 2026, Vol. 42 ›› Issue (6) : 651-657. DOI: 10.19538/j.fk2026060116

Clinical characteristics and pregnancy outcomes of patients with adnexal torsion during pregnancy: A single-center retrospective study

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Abstract

Objective To summarize and analyze clinical features, management, and outcomes of patients with adnexal torsion during pregnancy. Methods Retrospective analysis was conducted regarding the clinical data of 29 patients with adnexal torsion who were surgically confirmed at Beijing Chaoyang Hospital (March 2012-July 2024). Results Median age was 29 years (22-36), median gestational age at onset was 14 weeks (6-38), and the pregnancy trimesters were as follows: first 51.7%, second 24.1%, third 24.1%. The main symptoms included sudden abdominal pain (100.0%) and pelvic mass (86.2%), often accompanied by nausea (75.9%) and/or vomiting (55.2%). Laparoscopy accounted for 34.5% and laparotomy 65.5%. Conservative procedures (ovarian cyst enucleation, adnexal detorsion) accounted for 65.5% and adnexectomy 34.5%. There was no postoperative thrombosis or recurrence. There were 11 cases of full-term delivery, 3 abortions and 1 embryonic arrest at first trimester, 6 full-term and 1 preterm (14.3%) at second trimester, and 2 full-term and 5 preterm (71.4%) at third trimester. Conclusions Adnexal torsion during pregnancy mainly occurs in early-to-mid pregnancy, with sudden pain and nausea/vomiting as the typical symptoms, which requires prompt surgery. Conservative surgery is safe and ovary should be preserved as much as possible. Preterm risk is highest in third trimester.

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adnexal torsion / pregnancy / clinical characteristics / pregnancy outcome

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LI Meng-hui , ZHANG Zhi-qiang , LI Hua , et al . Clinical characteristics and pregnancy outcomes of patients with adnexal torsion during pregnancy: A single-center retrospective study[J]. Chinese Journal of Practical Gynecology and Obstetrics. 2026, 42(6): 651-657 https://doi.org/10.19538/j.fk2026060116

References

[1]
王玉东, 王建东, 刘淑娟, 等. 附件扭转诊治中国专家共识(2024年版)[J]. 中国实用妇科与产科杂志, 2024, 40(8):826-831.DOI:10.19538/j.fk2024080112.
[2]
李孟慧, 穆博然, 李华. 附件扭转临床特征及手术治疗一项12年299例患者的单中心回顾性研究[J]. 中华妇产科杂志, 2024, 59(11): 871-874. DOI:10.3760/cma.j.cn112141-20240518-00283.
[3]
Li M, Wang H, Hou S, et al. Comparison of characteristics and outcomes of premenopausal and postmenopausal women with adnexal torsion[J]. J Int Med Res, 2024, 52(12): 3000605241305251. DOI: 10.1177/03000605241305251.
This study aimed to compare the clinical characteristics and surgical and histological outcomes of premenopausal and postmenopausal patients with adnexal torsion.
[4]
Wang YX, Deng S. Clinical characteristics, treatment and outcomes of adnexal torsion in pregnant women: a retrospective study[J]. BMC Pregnancy Childbirth, 2020, 20(1): 483. DOI: 10.1186/s12884-020-03173-7.
Adnexal torsion during pregnancy is a gynecological emergency. Delayed diagnosis and treatment can cause ovarian necrosis and fetal loss. This study assessed the clinical characteristics, treatment and outcomes of adnexal torsion in pregnant women.
[5]
Melcer Y, Sarig-Meth T, Maymon R, et al. Similar but different: A comparison of adnexal torsion in pediatric, adolescent, and pregnant and reproductive-age women[J]. J Womens Health (Larchmt), 2016, 25(4): 391-396. DOI: 10.1089/jwh.2015.5490.
We sought to investigate and compare the clinical presentation, ultrasound findings, surgical characteristics, and causes of adnexal torsion among three groups: pediatric and adolescent population, reproductive-age women, and pregnant women.Two hundred twenty-seven surgically confirmed episodes of adnexal torsion in 199 patients treated in our department from January 2008 to December 2014 were retrospectively analyzed.Abdominal pain duration of >24 hours before emergency room presentation was more common in pediatric and adolescent patients compared with reproductive-age and pregnant women (42.3% vs. 28.4% and 15.5%, respectively, p = 0.04). However, there was no difference between the groups in the time interval from their emergency room admission to surgery. Torsion of "normal adnexa" occurred in 11/44 (25.0%) of pediatric and adolescent patients, 30/99 (30.3%) of reproductive-age patients, and 12/56 (21.4%) of pregnant patients, while torsion involving multicystic ovaries occurred in 0%, 4%, and 32.1%, respectively, torsion involving paraovarian cysts occurred in 20.5%, 14.1%, and 1.8%, respectively, and torsion involving benign dermoid cysts occurred in 4.5%, 15.2%, and 5.4%, respectively (p < 0.001). Torsion involving supposedly functional ovarian cysts occurred in 45.5%, 34.3%, and 69.6%, respectively (p < 0.001). The torsion recurrence rates were 18.2% in the pediatric subjects, 19.2% in reproductive-age women, and 10.7% in pregnant women (p = 0.3).The presentation of adnexal torsion is similar in pediatric and reproductive-age and pregnant women, although the underlying adnexal pathology may be different. Functional ovarian cysts cause the majority of torsion cases in pregnant women. Recurrence of torsion may occur in any age group.
[6]
郭晓玥, 赵扬玉. 妊娠期附件扭转-手术时机与方式[J]. 中国实用妇科与产科杂志, 2023, 39(4):403-406. DOI:10.19538/j.fk2023040106.
[7]
Bassi A, Czuzoj-Shulman N, Abenhaim HA. Effect of pregnancy on the management and outcomes of ovarian torsion: A population-based matched cohort study[J]. J Minim Invasive Gynecol, 2018, 25(7): 1260-1265. DOI:10.1016/j.jmig.2018.03.022.
[8]
Meller N, Levin G, Cohen A, et al. Surgically confirmed adnexal torsion during pregnancy: Does the trimester make a difference[J]. J Obstet Gynaecol Res, 2021, 47(12): 4216-4223. DOI: 10.1111/jog.15048.
To investigate the clinical and the sonographic characteristics of adnexal torsion (AT) during pregnancy and to underline differences in AT manifestation between pregnancy trimesters.
[9]
Didar H, Najafiarab H, Keyvanfar A, et al. Adnexal torsion in pregnancy: A systematic review of case reports and case series[J]. Am J Emerg Med, 2023, 65: 43-52. DOI: 10.1016/J.AJEM.2022.12.026.
[10]
Meyer R, Meller N, Komem DA, et al. Pregnancy outcomes following laparoscopy for suspected adnexal torsion during pregnancy[J]. J Matern Fetal Neonatal Med, 2022, 35(25): 6396-6402. DOI: 10.1080/14767058.2021.1914574.
[11]
Seo SK, Lee JB, Lee I, et al. Clinical and pathological comparisons of adnexal torsion between pregnant and non-pregnant women[J]. J Obstet Gynaecol Res, 2019, 45(9): 1899-1905. DOI: 10.1111/jog.14057.
We evaluated and compared the clinical and pathological differences between pregnant and non‐pregnant women with adnexal torsion.
[12]
Thiyagalingam S, Petrosellini C, Mellon C. Adnexal Torsion in the Third Trimester[J]. Cureus, 2024, 16(5): e60836. DOI: 10.7759/CUREUS.60836.
[13]
Lee JH, Roh HJ, Ahn JW, et al. The diagnostic accuracy of magnetic resonance imaging for maternal acute adnexal torsion during pregnancy: Single-Institution clinical performance review[J]. J Clin Med, 2020, 9(7): 2209. DOI: 10.3390/jcm9072209.
[14]
Gomes MM, Cavalcanti LS, Reis RL, et al. Twist and shout: magnetic resonance imaging findings in ovarian torsion[J]. Radiol Bras, 2019, 52(6): 397-402. DOI: 10.1590/0100-3984.2018.0079.
Adnexal torsion is characterized by partial or complete rotation of the suspensory ligament of the ovary and its corresponding vascular pedicle, resulting in vascular impairment that can culminate in hemorrhagic infarction, as well as necrosis of the ovary and fallopian tube. Because there are myriad causes of acute pelvic pain, the differential diagnosis of ovarian torsion is often challenging. Consequently, radiologists should be familiar with the main imaging findings. In this regard, there are typical signs of ovarian torsion on magnetic resonance imaging, including increased ovarian volume with stromal edema and peripheral distribution of the ovarian follicles, as well as thickening of the fallopian tube, an adnexal mass (causal factor) that shifts toward the midline, and the classic, pathognomonic “whirlpool sign”. The objective of this essay was to review and illustrate the various magnetic resonance imaging findings in ovarian torsion.
[15]
Dawood MT, Naik M, Bharwani N, et al. Adnexal torsion: Review of radiologic appearances[J]. Radiographics, 2021, 41(2): 609-624. DOI:10.1148/RG.2021200118.
Adnexal torsion is the twisting of the ovary, and often of the fallopian tube, on its ligamental supports, resulting in vascular compromise and ovarian infarction. The definitive management is surgical detorsion, and prompt diagnosis facilitates preservation of the ovary, which is particularly important because this condition predominantly affects premenopausal women. The majority of patients present with severe acute pain, vomiting, and a surgical abdomen, and the diagnosis is often made clinically with corroborative US. However, the symptoms of adnexal torsion can be variable and nonspecific, making an early diagnosis challenging unless this condition is clinically suspected. When adnexal torsion is not clinically suspected, CT or MRI may be performed. Imaging has an important role in identifying adnexal torsion and accelerating definitive treatment, particularly in cases in which the diagnosis is not an early consideration. Several imaging features are characteristic of adnexal torsion and can be seen to varying degrees across different modalities: a massive, edematous ovary migrated to the midline; peripherally displaced ovarian follicles resembling a string of pearls; a benign ovarian lesion acting as a lead mass; surrounding inflammatory change or free fluid; and the uterus pulled toward the side of the affected ovary. Hemorrhage and absence of internal flow or enhancement are suggestive of ovarian infarction. Pertinent conditions to consider in the differential diagnosis are a ruptured hemorrhagic ovarian cyst, massive ovarian edema, ovarian hyperstimulation, and a degenerating leiomyoma. RSNA, 2021.
[16]
Renganathan R, Subramaniam P, Deebika S, et al. Scoring system for predicting ovarian necrosis in adnexal torsion using an ultra-short optimized MRI protocol[J]. Abdom Radiol, 2023, 48(6): 2122-2130. DOI: 10.1007/S00261-023-03886-1.
[17]
Vincze MA, Németh G, Novák T. Laparoscopic management of adnexal torsion at 32th week of gestation[J]. Orv Hetil, 2021, 162(35): 1418-1421. DOI: 10.1556/650.2021.32165.
Összefoglaló. Terhességben az élettani és anatómiai változások miatt bizonyos patológiás szervi eltérések nem specifikus tünettannal járhatnak. A várandósság alatt fellépő hasi panaszok esetén lényeges felállítani a gyors és pontos diagnózist, a minél korábbi adekvát terápia érdekében. A klinikai tünetek hátterében többek között állhatnak szülészeti betegségek, illetve appendicitis, megnagyobbodott ovariumcysta, nephrolithiasis vagy diverticulitis is. Esetismertetésünkben egy 32 hetes gravida ellátását prezentáljuk, aki jobb alhasi panaszok miatt jelentkezett a Szegedi Tudományegyetem Szülészeti és Nőgyógyászati Klinikáján. A magzati paraméterek megfelelőek voltak. A klinikai vizsgálatok appendicitis gyanúját vetették fel, mely miatt laparoszkópia történt. Torquálódott jobb oldali tuba uterina miatt jobb oldali salpingectomiát végeztünk, az appendix kóros elváltozása nem igazolódott. Magzati, illetve anyai szövődmény a posztoperatív szakban nem volt. A további terhesgondozás során szövődményt nem észleltünk, majd a betöltött 40. terhességi héten hüvelyi úton egészséges újszülött született. A méhfüggelék megcsavarodásának operatív megoldása laparoszkópos úton alkalmazható módszernek tekinthető terhességben is. Az adnexcsavarodás ritka sürgősségi nőgyógyászati kórképnek számít, bár szakirodalmi adatok alapján az adnexum torsiójának rizikója fokozott lehet a terhesség korai szakaszában, kiváltképp asszisztált reprodukciós technikák alkalmazása esetén. Várandósság alatt hirtelen jelentkező alhasi panaszok esetén az anamnesztikus adatok tükrében, a klinikai vizsgálatok során szükséges az adnextorsio lehetőségére is gondolni. Orv Hetil. 2021; 162(35): 1418-1421. Summary. Due to physiological and anatomical changes in pregnancy, certain pathological organ abnormalities may be associated with non-specific symptoms. In the case of abdominal complaints during pregnancy, it is important to make a quick and accurate diagnosis to apply an early adequate therapy. The cause of the clinical symptoms can be obstetrical diseases, appendicitis, large ovarial cyst, rarely nephrolithiasis or diverticulitis. Through our case study, we present the treatment of a 32-week gravida. Examination of the pregnant patient occured at the Department of Obstetrics and Gynecology of the University of Szeged due to right lower abdominal pain. The fetal parameters were satisfactory. We assumed appendicitis, so after proper preparation laparoscopy was performed. Salpingectomy was performed because of torqued right fallopian tube and no pathological changes were detected on the appendix. In the postoperative period, there were no fetal or maternal complications. During further care of pregnancy, there were no complications and a healthy newborn was born by vaginal delivery at the 40th week of gestation. The operative procedure of adnexal rotation by laparoscopy can be considered as an applicable method even in pregnancy. Adnexal torsion is a rare emergency gynecological disease, although literature data suggest an increased risk in early pregnancy, especially in the case of assisted reproductive technology. In the case of sudden abdominal pain during pregnancy, in the light of anamnestic data, it is recommended to consider the possibility of adnexal torsion, too. Orv Hetil. 2021; 162(35): 1418-1421.
[18]
Takeda A, Hayashi S. Gasless laparoendoscopic single-site assisted extracorporeal ovarian cystectomy through the umbilicus for the management of ovarian torsion at 33 weeks of gestation: A case report with literature review[J]. Case Rep Womens Health, 2023, 38: e00517. DOI: 10.1016/J.CRWH.2023.E00517.
[19]
Indiran V. Additional signs and features of adnexal torsion[J]. Radiographics, 2022, 42(1): E31. DOI:10.1148/RG.210213.
[20]
Cathcart AM, Nezhat FR, Emerson J, et al. Adnexal masses during pregnancy: diagnosis, treatment, and prognosis[J]. Am J Obstet Gynecol, 2023, 228(6): 601-612. DOI: 10.1016/J.AJOG.2022.11.1291.
[21]
Ye P, Zhao N, Shu J, et al. Laparoscopy versus open surgery for adnexal masses in pregnancy: a meta-analytic review[J]. Arch Gynecol Obstet, 2019, 299(3): 625-634. DOI: 10.1007/S00404-018-05039-Y.
The objective of this meta-analysis is to investigate and compare the pregnancy outcomes of laparoscopy and open surgery in the treatment of ovarian tumors during pregnancy.Search was conducted using MEDLINE, EMBASE, and Cochrane Databases from January 1990 to November 2018. A broad search strategy was used to identify studies comparing laparoscopy and open surgery in pregnancy. Inclusion criteria included comparative studies with the quantitative outcome data on gravida. Two authors independently reviewed and assessed for the quality of included studies according to the Newcastle-Ottawa Scale. Data were extracted for fetal loss, preterm delivery, duration of surgery, blood loss and length of hospital stay.Nine retrospective trials were identified involving 985 patients. No statistical significance was found in fetal loss between laparoscopy and open surgery (P value = 0.334). The pooled estimate for preterm labor statistically significantly decreased for laparoscopy group (P value = 0.014). Reduced operative blood loss was found in laparoscopy group by 83.81 ml (P value = 0.015). Duration of operation may be longer in the laparoscopy group, but without statistical significance (P value = 0.346). Length of hospital stay was shorter in the laparoscopy group with reduction of 1.95 days (P value < 0.001).The available low-grade evidence suggests that laparoscopic surgery might be a feasible alternative for pregnant women with adnexal masses.
[22]
梁志清, 梁小龙. 单孔腹腔镜手术在妇科疾病诊治中的应用现状与争议[J]. 中国实用妇科与产科杂志, 2025, 41(7):773-678. DOI:10.19538/j.fk2025070101.
[23]
Takeda A, Kitami K, Shibata M. Magnetic resonance imaging and gasless laparoendoscopic single-site surgery for the diagnosis and management of isolated tubal torsion with a paratubal cyst at 31 weeks of gestation: A case report and literature review[J]. J Obstet Gynaecol Res, 2020, 46(8): 1450-1455. DOI: 10.1111/JOG.14252.
A 30‐year‐old nulliparous woman was transferred under suspicion of acute appendicitis, due to the sudden onset of severe right lower quadrant pain at 31 weeks and 4 days of gestation. Magnetic resonance imaging showed a cystic mass measuring 40 mm in diameter in the right lower abdomen. Because the right ovary without edematous swelling was noted adjacent to the cystic mass, isolated tubal torsion was strongly suspected. Emergency gasless laparoendoscopic single‐site surgery showed isolated torsion of the right fallopian tube with a paratubal cyst. The right ovary was not involved in this torsion. Because the color tone of the distal portion of the fallopian tube did not recover sufficiently after detorsion, right salpingectomy was performed. Postoperatively, the infusion of magnesium sulfate was initiated due to increased uterine contraction and continued until 36 weeks of gestation. At 38 weeks and 1 day of gestation, uneventful vaginal delivery yielded a healthy female infant.
[24]
Elci E. Laparoscopic management of a torsioned adnexal mass in the third trimester of pregnancy[J]. J Obstet Gynaecol Can, 2022, 44(4): 335-336. DOI: 10.1016/J.JOGC.2020.05.012.
[25]
Wu WF, Wang ZH, Xiu YL, et al. Characteristics and surgical invervention of ovarian torsion in pregnant compared with nonpregnant women[J]. Medicine (Baltimore), 2020, 99(24): e20627. DOI: 10.1097/MD.0000000000020627.
The aim of our study was to compare the clinical and surgical characteristics of pregnant and nonpregnant women with surgically verified ovarian torsion, as well as the differences among 3 trimesters during pregnancy.
[26]
Mandelbaum RS, Smith MB, Violette CJ, et al. Conservative surgery for ovarian torsion in young women: perioperative complications and national trends[J]. BJOG, 2020, 127(8): 957-965. DOI: 10.1111/1471-0528.16179.
To analyse populational trends and perioperative complications following conservative surgery versus oophorectomy in women <50 years of age with ovarian torsion.
[27]
Young RJ, Kho KA. Twist and shout: How can we do better for our patients with ovarian torsion[J]. Obstet Gynecol, 2023, 141(5): 886-887. DOI: 10.1097/AOG.0000000000005177.
[28]
Ekici H, Okmen F, Imamoglu M, et al. Perioperative outcomes in pregnant women who underwent surgery for adnexal torsion[J]. Rev Bras Ginecol Obstet, 2022, 44(4): 336-342. DOI: 10.1055/S-0042-1742403.
\n Objective To evaluate clinical characteristics, maternal and fetal outcomes in pregnant women who underwent surgery for adnexal torsion (AT).
[29]
郭晓玥, 赵扬玉. 妊娠期附件扭转——手术时机与方式[J]. 中国实用妇科与产科杂志, 2023, 39(4):403-406.DOI:10.19538/j.fk2023040106.
[30]
Dvash S, Pekar M, Melcer Y, et al. Adnexal torsion in pregnancy managed by laparoscopy is associated with favorable obstetric outcomes[J]. J Minim Invasive Gynecol, 2020, 27(6): 1295-1299. DOI: 10.1016/J.JMIG.2019.09.783.
[31]
祝彩霞, 蔡诗琴, 黄晓晴, 等. 妊娠期附件扭转手术治疗病例临床特点及妊娠结局分析[J]. 中山大学学报(医学科学版), 2023, 44(6): 1053-1069. DOI: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2023.0621.
[32]
Rottenstreich M, Rotem R, Hirsch A, et al. Maternal and perinatal outcomes following laparoscopy for suspected adnexal torsion during pregnancy: a multicenter cohort study[J]. Arch Gynecol Obstet, 2020, 302(6): 1413-1419. DOI: 10.1007/s00404-020-05752-7.
[33]
Djavadian D, Braendle W, Jaenicke F. Laparoscopic oophoropexy for the treatment of recurrent torsion of the adnexa in pregnancy: case report and review[J]. Fertil Steri, 2004, 82(4): 933-936. DOI: 10.1016/j.fertnstert.2004.03.048.

Footnotes

利益冲突 所有作者均声明不存在利益冲突

Funding

2020 National and Provincial Clinical Key Specialty Capacity Building Project(Gynecology,2-1-2-ylfw)
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